introduction worldwide, chronic liver disease is a major cause of morbidity and mortality. causes of elevated serum alanine aminotransferase (alt) levels vary depending on the population under study. the aim of this study is to evaluate the frequency and causes of persistently elevated alt levels in patients of the gastroenterology (gi) clinics in ghaem and emam reza hospitals in mashhad, iran....

background :timely diagnosis of liver cirrhosis is vital for preventing further liver damage and giving the patient the chance of transplantation. although biopsy of the liver is the gold standard for cirrhosis assessment, it has some risks and limitations and this has led to the development of new noninvasive methods to determine the stage and prognosis of the patients. we aimed to design an a...

background: although several observational and experimental studies have examined the effects of low carbohydrate diets (lcds) on nonalcoholic fatty liver disease (nafld), there are considerable inconsistencies among studies. we summarized the effect of lcds on liver function tests, including intrahepatic lipid content (ihlc), alanine transaminase (alt), aspartate aminotransferases (ast),and ga...

PURPOSE The aim of this study was to investigate the influence of variations in fatty liver on the ultrasonographic detection of focal liver lesions. METHODS A total of 229 patients with varying degrees of fatty liver and focal liver lesions and 200 patients with focal liver lesions but no fatty liver were randomly selected for inclusion in groups I and II, respectively. Findings of focal liv...

nonalcoholic fatty liver disease (nafld) is one of the aspects of metabolic syndrome (mets). due to the increase of mets in iran, this study was conducted to determine the prevalence of nafld, its potential predictors and their sex distribution in north of iran, amol.in 2008 this population based cross-sectional study included 5023 adult individuals who were randomly selected from amol healthca...

background a strong association between obesity and non-alcoholic fatty liver disease (nafld) has been reported. objectives this study was conducted to evaluate if new obesity indices, including a body shape index (absi) and body roundness index (bri), have stronger associations with nafld than waist-to-hip ratio (whr) and waist-to-height ratio (whtr). methods in this cross-sectional study, we ...

nonalcoholic fatty liver disease (nafld) is an obesity-associated disease and dysregulation of adipokines has an important role in its development. omentin-1 (itln1 protein) and resistin are two adipokine secreted from adipose tissue. single nucleotide polymorphisms in the adipokine genes may affect expression and activity of the adipokine, and thus play a contributory role in nafld pathogenesi...