The envelope glycoprotein (gp70) of a molecularly cloned, replication-defective feline leukemia virus (FeLV-FAIDS clone 61C) carries determinants for induction of fatal immunodeficiency disease, whereas the gp70 of its companion replication-competent, probably parent virus (clone 61E) does not. Immunoprecipitation analysis of the extracellular glycoproteins of 61E and EECC, a replication-compet...

the purpose of this study was to investigate magnetic resonance imaging (mri) of the normal feline eyeand optic nerves using t1-weighted and t2-weighted images. a total of 6 healthy female domestic short haircats age 2-2.5 years and weighing 3.2 ± 0.4 kg were selected. magnetic resonance imaging data werecollected using gemsow (philips) at a magnetic field strength of 1.5 t. dorsal, sagittal, a...

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feline leukemia virus is a retrovirus of domestic cats that occurs throughout the world. persistent infection in the animals and persistently infected cats are at risk for developing of fatal diseases such as: lymphoma, leukemia, haematopoietic malignancies and anemia. in this study as the first time in iran the serologic prevalence of feline leukemia virus was determined with commercial elisa ...

Complementarity between nucleotides at the 5' terminus of tRNA(Lys,3) and the U5-IR loop of the feline immunodeficiency virus RNA genome suggests a novel intermolecular interaction controls initiation of minus strand synthesis in a manner analogous to other retroviral systems. Base pairing of this tRNA-viral RNA duplex was confirmed by nuclease mapping of the RNA genome containing full-length o...

The main feature of feline coronavirus infection is its manifestation in the form peritonitis. Feline infectious peritonitis a highly lethal disease that lacks primary prevention and therapy. Therefore, an epizootic problem near future. In our review, we demonstrate current clinical, diagnostic, therapeutic interventions for peritonitis, as well hypotheses origin.

In addition to their role in reverse transcription, the R-region sequences of some retroviruses affect viral transcription. The first 28 nucleotides of the R region within the long terminal repeat (LTR) of the murine type C retrovirus SL3 were predicted to form a stem-loop structure. We tested whether this structure affected the transcriptional activity of the viral LTR. Mutations that altered ...

Gardner-Rasheed feline sarcoma virus (GR-FeSV) is an acute transforming retrovirus which encodes a gag-onc polyprotein possessing an associated tyrosine kinase activity. The integrated form of this virus, isolated in the Charon 21A strain of bacteriophage lambda, demonstrated an ability to transform NIH/3T3 cells at high efficiency upon transfection. Foci induced by GR-FeSV DNA contained rescua...