fibrosis is the pathological condition resulting in the growth of excess fibrous connective tissue in an organ or body system as a reparative or reactive process. in the field of clinical pathology, clinicians and medical scientists are endeavoring to translate experimental knowledge into effective, innovative treatments for a range of fibrotic conditions. the amelioration of whole organ functi...

background nonalcoholic fatty liver disease (nafld) is being increasingly recognized as a cause of chronic liver disease. it has also been associated with devastating outcomes such as decompensated liver cirrhosis and hepatocellular carcinoma, as well as diabetes and metabolic syndrome. objectives this study was conducted in order to assess liver fibrosis using fibroscan, and to compare these r...

objective(s):  more than 1500 registered mutations in cystic fibrosis transmembrane regulator (cftr) gene are responsible for dysfunction of an ion channel protein and a wide spectrum of clinical manifestations in patients with cystic fibrosis (cf). this study was performed to investigate the frequency of a number of well-known cftr mutations in north eastern iranian cf patients. material and m...

idiopathic retroperitoneal fibrosis is a rare disorder of an unknown etiology characterized by an inflammatory proliferative fibrosing process that may involve the ureters in 80-100% of cases. â the present study was carried on a 38 years old man who was admitted to imam khomeini hospital with severe abdominal pain and renal failure. abdominal mri showed encasement of abdominal aorta and bilate...