In this paper an ensemble feature extraction algorithm is proposed based on Adaboost.M2 for multiclass classification problem. The proposed algorithm makes no assumption about the distribution of the data and primarily performs by directly selecting the discriminant features with the minimum training error, which can overcome the main drawbacks of the traditional methods, such as Principle Comp...

Human familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is characterized by low HDL, accumulation of an abnormal cholesterol-rich multilamellar particle called lipoprotein-X (LpX) in plasma, and renal disease. The aim of our study was to determine if LpX is nephrotoxic and to gain insight into the pathogenesis of FLD renal disease. We administered a synthetic LpX, nearly ide...

Abstract We examine the impact of audit committee (AC) characteristics (e.g. AC foreign members, female members with multiple directorships, share ownership and financial supervisory expertise) on forward-looking disclosure (FLD) quality quantity. Using a sample Omani companies listed Muscat Securities Market over five-year period (2014–2018), we find that number (such as size, directorships) i...

Sheet metal forming boundaries are established using the limit diagram (FLD). The Nakajima and Marciniak tests, which based on stretching a material punch, most commonly used methods for determining FLD or fracture (FFLD). results usually evaluated by calculating local strain, strain rates, specimen thickness reduction strain. When amount of experimental is insufficient, miniaturization testing...

We describe a method for sparse feature selection for a class of problems motivated by our work in Computer-Aided Detection (CAD) systems for identifying structures of interest in medical images. Typical CAD data sets for classification are large (several thousand candidates) and unbalanced (significantly fewer than 1% of the candidates are ”positive”). To be accepted by physicians, CAD systems...

Several prediction models for fatty liver disease (FLD) are available with limited externally validation and less comprehensive evaluation. The aim was to perform external validation and direct comparison of 4 prediction models (the Fatty Liver Index, the Hepatic Steatosis Index, the ZJU index, and the Framingham Steatosis Index) for FLD both in the overall population and the obese subpopulatio...

Histone acetylation and deacetylation play an important role in epigenetic controls of gene expression. HISTONE DEACETYLASE6 (HDA6) is a REDUCED POTASSIUM DEPENDENCY3-type histone deacetylase, and the Arabidopsis (Arabidopsis thaliana) hda6 mutant axe1-5 displayed a late-flowering phenotype. axe1-5/flc-3 double mutants flowered earlier than axe1-5 plants, indicating that the late-flowering phen...

BACKGROUND The aim of our study was to determine the relation of alcohol consumption and cigarette smoking on continuous-measured hepatic fat fraction (HFF) in a population free of cardiovascular disease. We suggested a direct correlation of alcohol consumption with HFF and increased HFF in former smokers compared to current smokers. METHODS Data from 384 subjects (mean age: 56 years, 58% men...

Fatty liver is a common feature of both obesity and lipodystrophy, reflecting compromised adipose tissue function. The lipin-deficient fatty liver dystrophy (fld) mouse is an exception, as there is lipodystrophy without a fatty liver. Using a combination of indirect calorimetry and stable-isotope flux phenotyping, we determined that fld mice exhibit abnormal fuel utilization throughout the diur...