We propose a flexible joint longitudinal-survival framework to examine the association between longitudinally collected biomarkers and time-to-event endpoint. More specifically, we use our method for analyzing survival outcome of end-stage renal disease patients with time-varying serum albumin measurements. Our proposed method is robust to common parametric assumptions in that it avoids ex...

As the key connecting part of rigid flexible coupling manipulator, structural dynamic characteristics bolted joint are analyzed by using simulation technology pro/e and ANSYS. Based on spring equivalent principle, finite element model bolt is established, relationship equation between contact surface pressure preload derived, its stress state analyzed; micro convex deformation Hertz theory, tan...