Received 7/16/2008; revised 9/5/2008; accepted 9/8/2008. For correspondence and reprints contact: Ming-Hsien Lin, M.D., Division of Nuclear Medicine, Taipei City Hospital Zhongxiao Branch. 87 Tonde Road, Nangang District, Taipei 115, Taiwan, Tel: (886)2-27861288 ext. 8089, Fax: (886)2-26534501, E-mail: [email protected] Previous reports stated that patients with coronary artery fistula (CAF) a...

AIMS Human atrial electrophysiology exhibits high inter-subject variability in both sinus rhythm (SR) and chronic atrial fibrillation (cAF) patients. Variability is however rarely investigated in experimental and theoretical electrophysiological studies, thus hampering the understanding of its underlying causes but also its implications in explaining differences in the response to disease and t...

Rapid atrial pacing causes electrical remodeling that leads to atrial fibrillation (AF). AF can further remodel atrial electrophysiology to maintain AF. Our previous studies showed that there was a marked difference in the duration of AF in dogs that have been atrial paced at 400 beats/min for 6 wk. We hypothesized that this difference is based on the changes in the degree of electrical remodel...

Co-array notation provides a compact syntax for programming parallel programs. Co-array Fortran (CAF) introduced and implements this notation, and CAF is currently proposed as an extension to the Fortran language standard. We believe that co-array notation requires a revised semantic definition beyond that specified by CAF for both pragmatic reasons within Fortran and to make the notation attra...

Stromal fibrosis is a prominent histologic characteristic of pancreatic ductal adenocarcinoma (PDAC), but how stromal fibroblasts are regulated in the tumor microenvironment (TME) to support tumor growth is largely unknown. Here we show that PDAC cells can induce DNA methylation in cancer-associated fibroblasts (CAF). Upon direct contact with PDAC cells, DNA methylation of SOCS1 and other genes...

The histone chaperones CAF-1 and Rtt106p are required for heterochromatin silencing in the yeast Saccharomyces cerevisiae. Although it has been suggested that CAF-1 is involved in the maintenance of heterochromatin silencing, their exact functions during this process are not well understood. Here, we show that CAF-1 and Rtt106p are involved in the early stages of heterochromatin formation. The ...

RATIONALE Coronary artery fistula (CAF) is characterized by an abnormal communication of a coronary artery with a cardiac chamber or a great vessel bypassing the capillary bed. Surgical closure of large or symptomatic CAF is the gold standard treatment. However the previously closed CAF still has the possibility to reopen. Superior vena cava syndrome (SVCS) is defined as a condition that occurs...

Histone synthesis and chromatin assembly are mainly associated with DNA replication and are thus intimately involved in cell cycle regulation. The expression of key components involved in these events in human cells was studied in relation to cell-proliferative status. Among several chromatin assembly factors, chromatin assembly factor (CAF)-1 stood out as the most discriminating marker of the ...

Coronary artery fistulae (CAF) represent the most frequent congenital anomalies influencing hemodynamic parameters of coronary arteries. However, CAF complicated with a huge aneurysm does not frequently occur. Determining the optimal management of symptomatic patients with CAF and aneurysm still remains a challenging problem, and has been traditionally considered as an indication for cardiac su...

Single task writing assessments used in longitudinal studies have raised concerns regarding their reliability. By means of Generalizability Theory (GT), this study investigated the reliability L2 scored on different CAF measures, focusing a) single and effects b) topics c) task-taking occasions assessment We analytic quantitative scores obtained from five measures through a 1-day dataset 21-day...