BACKGROUND There are concerns that altered thyroid functioning could be the result of ingesting too much fluoride. Community water fluoridation (CWF) is an important source of fluoride exposure. Our objectives were to examine the association between fluoride exposure and (1) diagnosis of a thyroid condition and (2) indicators of thyroid functioning among a national population-based sample of Ca...

Wistar albino rats were exposed to 30 or 100 ppm fluoride in drinking water during their fetal, weanling and post-weaning stages of life up to puberty. Extent of lipid peroxidation and response of the antioxidant systems in red blood cells and plasma to prolonged fluoride exposure were assessed in these rats in comparison to the control rats fed with permissible level (0.5 ppm) of fluoride. Rat...

The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding ...

The range of fluoride levels in the drinking-water of cities and villages in South Africa was determined during the transition from a very dry (1983) to a wet (1984/85) period. The combination fluoride ion selective electrode was employed for the determination of the fluoride concentration. It was found that fluoride levels in drinking-water changed for 93% of the cities and villages studied du...

376 three-year old children were divided into four experimental groups and exposed to different combinations of preventive programs for a period of two years. All the groups were given the same basic prophylactic information. Additionally Group I received fluoride tablets (FLUDENT) for daily sucking twice a day plus a placebo dentifrice free of fluoride. Group II was given a fluoride dentifrice...

Wistar rats were given 20 ppm fluoride in drinking water, or single administration of 115 mg/kg alloxan i.m. to induce diabetes, or single administration of 115 mg/kg alloxan i.m. followed by 20 ppm fluoride for 31 days. Blood sugar level increased in rats given alloxan and alloxan + fluoride. Body weight gain in rats given alloxan + fluoride decreased significantly compared to other groups. De...

The Present investigation covers the scientific comprehension of the potential effects of fluoride toxicity on body and testes weight and the spermatozoal activities in male albino rat and the beneficial effect of novel medicinal plant Tamarindus indica therapeutic treatment (10gm/kg body weight) after fluoride water intoxication. Three groups of male albino rats five of each were intoxicated w...

Sir, Ludlow et al. [1] only confirmed that our knowledge of the potential adverse effects of chronic low fluoride supplementation of drinking water on normal or diseased kidneys is insufficient. More than 60 years after water fluoridation, there is no high-level evidence as most published studies are small, have methological deficiencies or are otherwise flawed. There are two areas of concern r...

In a double-blind trial with monofluorophosphate (25 mg fluoride per day) given to 460 aged persons (237 treated, 233 control) for eight months no difference was observed in height, admission to hospital, or mortality. Fractures and exacerbation of arthrosis were more frequent in the fluoride group. Vertebral x-ray films showed no difference. The free ionized fluoride levels in the plasma of th...

Water fluoridation is unnatural. It is particularly inappropriate to put fluoride into the public drinking water because fluoride is not an essential nutrient. Not one single process in the human body needs fluoride to function properly. Nature has given its own verdict on the lack of need for fluoride. The level in mothers’ milk is extremely low (0.004 ppm , NRC, 2006, p.40). That’s right fluo...