The inhibition of acetylcholinesterase and other hydrolytic enzymes by methanesulfonyl fluoride, other sulfonyl fluorides, and anhydrides of methanesulfonic acid has been studied by several workers (2-5). Certain alkyl ammonium ions greatly increase the rate of irreversible inhibition of acetylcholinesterase by methanesulfonyl fluoride (6). The inhibition arises from the formation of a specific...

a flow injection system is reported for the determination of fluoride based on its effects on the fluorescence intensity of al-morin complex at ph 3.0 in ethanol-warn mixture. the effect of important parameters such as excitation and emission wavelengths, ph, reagents concenkations, flow rate of the carrier stream, sample injection volume, time of measurepent and interferences are reported. cat...

presence of available and stable fluoride in a dentifrice formulation is a major requirement for an anti-caries effect. although the available fluoride concentration in iranian dentifrices has been reported in previous studies, there is little information on its stability; which is dependent upon dentifrice formulation. this study was done to assess the fluoride ion concentration and stability ...

The presence of fluoride ions in drinking water plays an important role in human health. For that reason, maintaining the optimum concentration of fluoride ions in drinking water is essential, as both low and excess (above the permissible level) concentrations can cause different health problems, such as fluorosis, urolithiasis, kidney failure, cancer, and can even lead to death. So, developmen...

Bacillus subtilis, Neisseria subflava, and LYT coccus were found to undergo massive lysis after growth in media containing 0.01 to 10 mM NaF. When cells of these organisms were transferred from late-exponential-phase cultures to 0.02 M sodium phosphate buffer plus 0.1 M KCl, they underwent spontaneous autolysis. Cells grown in media with fluoride were more liable to autolysis, and walls isolate...

Available literature on sodium monofluorophosphate and sodium fluoride suggests that sodium monofluorophosphate is hydrolysed in fluoride and phosphate ions and the Panel concludes that fluoride bioavailability will be to an extent comparable to the one from sodium fluoride. The most sensitive effect of fluoride exposure in humans is dental fluorosis and conclusions of comprehensive evaluations...

We describe a pretreatment method before determining the total fluoride in solutions containing tetrafluoroborate ion (BF(4)(-)) with ion-selective electrodes (ISEs). BF(4)(-) was quantitatively converted to free fluoride by reacting with aluminum ions. The total fluoride concentration was then determined by ISE analysis without preliminary steam distillation using a tartrate- and tris(hydroxym...

1. Series of colorimetric dynamic assays allowed the study of the inhibition of cholinesterases by F(-) ions in vitro, by using, as sources of enzyme, whole human blood, human serum, homogenized rat brain and two preparations of red blood cells (human and bovine) whose enzymic purity was ascertained. 2. The first evidence of inhibition of human serum pseudocholinesterase by fluoride was noticed...