OBJECTIVE To assess the short-term outcome in patients with high-risk prostate cancer treated by transrectal high-intensity focused ultrasound (HIFU). PATIENTS AND METHODS From April 2003 to November 2004, 30 patients with high-risk prostate cancer were enrolled in this prospective study; all had transurethral resection of the prostate before transrectal HIFU treatment, using the Ablatherm de...

Manual palpation is a common and very informative diagnostic tool based on estimation of changes in the stiffness of tissues that result from pathology. In the case of a small lesion or a lesion that is located deep within the body, it is difficult for changes in mechanical properties of tissue to be detected or evaluated via palpation. Furthermore, palpation is non-quantitative and cannot be u...

INTRODUCTION Focal therapy offers the possibility of cancer control, without the side effect profile of radical therapies. Early single centre prospective development studies using high intensity focused ultrasound (HIFU) have demonstrated encouraging genitourinary functional preservation and short-term cancer control. Large multi-centre trials are required to evaluate medium-term cancer contro...

Tissue-mimicking materials (TMMs) can provide a convenient, stable, and reproducible means for testing high intensity focused ultrasound (HIFU) devices. When TMMs containing thermal sensors are used to measure ultrasound-induced temperature rise, it is important that measurement results reasonably represent those that occur in biological tissue. Therefore the aim of this paper is to compare the...

The potential of high‐intensity focused ultrasound (HIFU) will not be realized unless the effects of overlaying tissues are understood in such a way that allows for estimation of HIFU dose distribution at a target tissue. We employ computational models to examine the impact of phase aberration on tissue ablation. Thompson and Roberts have recently studied the effects of phase aberration on ultr...

High intensity focused ultrasound (HIFU) is a promising technology for cancer treatment. Thereby, heating due to the focusing of the ultrasound non-invasively destroys the tumors. At the present state, the method is clinically restricted to uterine fibroids, adenomyosis, bone metastasis and prostate cancer. In abdominal organs as e.g. the liver, the motion due to breathing causes problems for t...

BACKGROUND Thermal and mechanical high intensity focused ultrasound (HIFU) ablation techniques are in development for non-invasive treatment of cancer. However, knowledge of in vivo histopathologic and immunologic reactions after HIFU ablation is still limited. This study aims to create a setup for evaluation of different HIFU ablation methods in mouse tumors using high-field magnetic resonance...

having in mind the high level of challenge in writing as a foreign language, this research provided iranian efl learners with audiovisual feedbacks as an alternative of common written feedback and focused on its’ meaningfulness in order to provide an incentive medium for the participants and increase their moti-vation. one hundred young adult female learners in addition to six english language ...

this experimental study examined the effectiveness of using focused and unfocused tasks on iranianintermediate efl learners’ performance in producing noun, adjective, and adverb clauses. in addition,the aim of this study was to explore the effects of form-focused instruction and the feedback studentsreceived from their teacher after doing focused grammar tasks. data consisted of the scores ofth...

anxiety is one of the most common reactions that parents show while understanding their children's intellectual disability due to down syndrome. anxiety leads parents not to develop appropriate relations with their children, subsequently their psychological health are at risk. the present study was aimed to determine the effect of problem-focused coping strategy training on psychological sympto...