A localized change in a protein, which occurs as a result of either ligand binding or single amino acid substitution, necessarily encounters the conformational uctuation of the rest of the protein. Both the entropy and the enthalpy associated with the change consist of contributions from uctuations in the atoms surrounding the localized site, but they compensate. A novel thermodynamic ensemble ...

The thermodynamic parameters for the intercalative interaction of structurally related well known intercalators, 9-aminoacridine (9AA) and proflavine (PF) were determined by means of fluorescence quenching study. The fluorescence intensity of 9AA decreased upon intercalation to DNA, poly[d(A-T)2] and poly[d(G-C)2]. A van’t Hoff plot was constructed from the temperature-dependence of slope of th...

thermal denaturation of a-lactalbumin in the absence and presence of various concentrations of sucrose,sorbitol, glucose and galactose as sugar osmolytes were measured by monitoring changes in the absorptions thatcarried out in a lambd 35 uv-vis double beam spectrophotometer at ph 6.0. these measurements gave valuesof t., (midpoint of denaturation), ah., (enthalpy change at t.), and acp (consta...

Due to their excellent thermophysical properties and high stability, inorganic salts Forsalt mixtures are considered promising thermal energy storage materials for applications operating at temperatures. A mixture of binary salts, such as CaCl2 (58 wt.%)-LiCl (42 wt.%), was investigated in this work understand stability use TES systems. Thermophysical properties, onset melting crystallization t...

The exceptionally high temperature sensitivity of certain transient receptor potential (TRP) family ion channels is the molecular basis of hot and cold sensation in sensory neurons. The laws of thermodynamics dictate that opening of these specialized TRP channels must involve an unusually large conformational standard-state enthalpy, ΔH(o): positive ΔH(o) for heat-activated and negative ΔH(o) f...

In this investigation thermochemical properties of 3-hydroxyphthalic anhydride were determined. Fusion enthalpy, fusion temperature and molar heat capacity in solid phase obtained by differential scanning calorimetry. By the Knudsen effusion method, enthalpy sublimation at 298.15 K was obtained. thermogravimetric data, it possible to determine vaporization. On other hand, formation determined c...