Fusarium Graminearum is responsible for Fusarium head blight (FHB) infection which reduces world-wide cereal crop yield. As a consequence of mycotoxin production in cereal grain, it has also serious negative impact on both human and animal health. The main objective of this study is to develop a mechanistic and conceptual metaphor of Fusarium growth. Our model is based on a new realization of G...

ABSTRACT Fusarium spp. in maize can contaminate the grain with mycotoxins if environmental conditions are favorable for fungal growth. To quantify the relationship between growth of Fusarium spp. and environmental conditions, a mathematical model was developed to simulate growth of F. graminearum and F. verticillioides on maize ears following silk inoculation in field experiments from 1992 to 1...

Arginine methylation of non-histone proteins by protein arginine methyltransferase (PRMT) has been shown to be important for various biological processes from yeast to human. Although PRMT genes are well conserved in fungi, none of them have been functionally characterized in plant pathogenic ascomycetes. In this study, we identified and characterized all of the four predicted PRMT genes in Fus...

The cereal pathogen Fusarium graminearum is the primary cause of Fusarium head blight (FHB) and a significant threat to food safety and crop production. To elucidate population structure and identify genomic targets of selection within major FHB pathogen populations in North America we sequenced the genomes of 60 diverse F. graminearum isolates. We also assembled the first pan-genome for F. gra...

This study was conducted to improve the knowledge of molecular processes involved in the interaction between Fusarium graminearum and emmer in the course of grain ripening. Emmer plants were artificially inoculated with a F. graminearum spore suspension at anthesis. In the course of grain ripening from milk ripe to plant death stage, grains at four phenological growth stages were collected for ...

UNLABELLED SUMMARY The rapid global re-emergence of Fusarium head blight disease of wheat and barley in the last decade along with contamination of grains with mycotoxins attributable to the disease have spurred basic research on the fungal causal agent. As a result, Fusarium graminearum quickly has become one of the most intensively studied fungal plant pathogens. This review briefly summarize...

Agmatine and other putrescines are known for being strong inducers of deoxynivalenol (DON) production in Fusarium graminearum. Other important species produce DON and/or other trichothecene type B toxins (3 acetylated DON, 15 acetylated DON, Fusarenon-X, Nivalenol), such as F. culmorum and F. poae. In order to verify whether the mechanism of the regulation of trichothecene type B induction by a...

Mycotoxins are secondary metabolites produced by fungi that when ingested at low concentrations are harmful to human and animal health. Toxins from Fusarium graminearum [deoxynivalenol (DON), zearalenone (ZEA)] are commonly found in wheat, barley and corn and their derived products. In Ontario, widespread occurrences of mycotoxins and substantial economic losses have occurred during periodic ep...

In the two fungal pathogens Fusarium fujikuroi and Fusarium graminearum, secondary metabolites (SMs) are fitness and virulence factors and there is compelling evidence that the coordination of SM gene expression is under epigenetic control. Here, we characterized Ccl1, a subunit of the COMPASS complex responsible for methylating lysine 4 of histone H3 (H3K4me). We show that Ccl1 is not essentia...