We describe Pyomo, an open source tool for modeling optimization applications in Python. Pyomo can be used to define symbolic problems, create concrete problem instances, and solve these instances with standard solvers. Pyomo provides a capability that is commonly associated with algebraic modeling languages such as AMPL, AIMMS, and GAMS, but Pyomo’s modeling objects are embedded within a full-...

Economic load dispatch (ELD) problem between power plant units is formulated as a nonlinear optimization with continuous variables. The main target in this problem is optimum planning in power plant units with minimum cost while equal and non-equal constraints consisting load request and unit production capacity are followed. In this paper an effective method based on particle swarm algorithm o...

We show how to implement the cross-validation technique used in machine learning as a slice model. We describe the formulation in terms of support vector machines and extend the GAMS/DEA interface to allow for efficient solutions of linear, mixed integer and simple quadratic slice models under GAMS.

Malignant gliomas contain stroma and a variety of immune cells including abundant activated microglia/macrophages. Mounting evidence indicates that the glioma microenvironment converts the glioma-associated microglia/macrophages (GAMs) into glioma-supportive, immunosuppressive cells; however, GAMs can retain intrinsic anti-tumor properties. Here, we review and discuss this duality and the poten...

Gliomas are the most commonly diagnosed primary tumors of the central nervous system (CNS). Median times of survival are dismal regardless of the treatment approach, underlying the need to develop more effective therapies. Modulation of the immune system is a promising strategy as innate and adaptive immunity play important roles in cancer progression. Glioma associated microglia and macrophage...

GAMs oscillate between states of strong rotation and up-down asymmetric plasma compression. Hence, at first glance the natural turbulent drive (or damping) mechanisms for them is either a direct boost of the rotation – via Reynolds stress – or the creation of asymmetric pressure distributions – via transport. However, an up-down asymmetric pressure can also be created by the divergence of the d...

The Gas and Aerosol Measurement Sensor (GAMS) was deployed aboard the NASA DC-8 aircraft during the second SAGE III Ozone Loss and Validation Experiment (SOLVE II). GAMS acquired line-of-sight (LOS) direct solar irradiance spectra during the sunlit portions of ten science flights of the DC-8 between 12 January and 4 February 2003. Differential line-of-sight (DLOS) optical depth spectra are prod...

We describe a framework for modeling optimization problems for solution on a grid computer. The framework is easy to adapt to multiple grid engines, and can seamlessly integrate evolving mechanisms from particular computing platforms. It facilitates the widely used master/worker model of computing and is shown to be exible and powerful enough for a large variety of optimization applications. In...