AIM To investigate the relationship between plasma ghrelin level, Helicobacter pylori (H. pylori) infection status and the severity of atrophy in hemodialysis patients. METHODS One hundred eights patients who received hemodialysis and 13 non-hemodialysis H. pylori-negative controls underwent gastroduodenoscopy to evaluate the severity of gastric atrophy. Serum levels of pepsinogen (PG) were m...

Aim: The aim of this study was to determine the histological findings H-pylori in diabetic patients. Material and methods: This observation conducted on 90 patients with infection at Gastroenterology Department, Nishtar Medical University, Multan duration from November, 2022 April, 2023. Endoscopic were determined. Chi Square test applied P value less than 0.05. Results: mean age 53.73±8.66 yea...

BACKGROUND Gastric cancer is increasingly recognized in Zambia. Although nutritional factors contribute to gastric cancer risk, their effect in Zambia is unknown. OBJECTIVE The objective was to investigate the association between intake of dietary antioxidants, urinary 8-iso prostaglandin F2α (8-iso PGF2α) as a marker of oxidative stress, and gastric cancer. DESIGN This was a case-control s...

Ménétrier’s disease (MD) is included in the group of hypertrophic gastropathy; is a rare gastric hyperplasia that affects adults and children, with different behavior between these groups. We know that its etiology is related to allergens and co-infections. It’s characterized by the hypertrophy of the gastric folds, with the appearance of cerebral convolutions on Upper Gastrointestinal Endoscop...

S hould Helicobacter pylori infection be eradicated in patients requiring maintenance proton pump inhibitor therapy for gastro-oesophageal reflux disease? This question has stimulated heated debate and contention over the past few years. The issue first came to prominence in 1996 when Kuipers et al published their study purporting to demonstrate that omeprazole accelerated the development of co...

OBJECTIVE To note the association of Helicobacter pylori in patients having carcinoma of stomach. METHODS A descriptive study was carried out at the Department of Histopathology, Ziauddin Medical University, Karachi from April 1992 to May 1998. Histological evaluation of 50 cases of carcinoma of stomach was compared with 50 cases each of chronic gastritis and histological normal gastric mucos...

Helicobacter pylori plays major causative roles in peptic ulcer disease and gastric cancer. Elevated acid secretion in patients with duodenal ulcers (DUs) contributes to duodenal injury, and diminished acid secretion in patients with gastric cancer allows carcinogen-producing bacteria to colonize the stomach. Eradication of H. pylori normalizes acid secretion both in hyper-secreting DU patients...

BACKGROUND Bile acid and Helicobacter pylori (H. pylori) are important toxic factors for gastric mucosal injury. We examined the role of bile acid in promoting histologic gastritis and gastric carcinoma in Japanese patients. METHODS A total of 767 patients (452 men, mean age 51.1 years) were studied. Gastric juice was collected by gastro-endoscopic examination, and the bile acid concentration...