BACKGROUND Previous studies have revealed the significance of Helicobacter pylori (H. pylori) infection as a risk factor of gastric cancer. Cytotoxin-associated gene A (cagA) positivity has been demonstrated to determine the clinical outcome of H. pylori infection in the presence of SHP-2 (src homology 2 domain-containing protein tyrosine phosphatase-2). This study aimed to examine the formerly...

Gastric cancer remains a leading cause of cancer-related deaths in many parts of the world. At present, prevention seems to be the most effective means to reduce its the incidence and mortality rate. Gastric atrophy is considered the first relevant step in the histogenesis of gastric adenocarcinoma. However, whether screening for and surveillance of atrophic gastritis is advisable is debated. T...

The purpose is to elucidate factors related to negative results of anti-H. pylori antibody test in cases with gastric mucosal atrophy. A total of 859 individuals without past history of eradication therapy for H. pylori (545 males, 314 females; mean age 52.4 years) who underwent an upper GI endoscopy examination and serological test were enrolled as subjects. Serological testing was performed u...

Background. Since gastrointestinal stromal tumor (GIST) is a mesenchymal submucosal tumor, the endosonographic, CT, and MRI features of gastric GISTs have been widely investigated. However, the GIST-bearing gastric mucosa status has not been reported. Objective. To characterize the GIST-bearing gastric mucosa status in terms of the degree of inflammation and atrophy, assessed endoscopically. Su...

PURPOSE Chronic Gastritis is the most common manifestation of infection with Helicobacter pylori. Changes in the gastric mucosa have tendency to progress towards mucosal atrophy, most likely in patients with gastric ulcer. We have explored the frequency of the presence of atrophic gastritis in patients with gastric and duodenal ulcers. MATERIAL AND METHOD We included 175 patients in a prospec...

Background: Endoscopic gastric atrophy according to Kimura-Takemoto classification has been shown be closely related histopathological atrophy. Gastric and intestinal metaplasia are considered precancerous lesions that need assessed monitored for early detection of dysplasia cancer, especially in H. pylori infected patients. The aim this study was evaluate the associations between these endosco...

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BACKGROUND The relationship between Helicobacter pylori and reflux oesophagitis remains controversial. AIMS To evaluate the relationship between H pylori and reflux oesophagitis in a large number of Japanese subjects. SUBJECTS A total of 5732 consecutive Japanese subjects during a health screening were enrolled. METHODS Gastrointestinal endoscopy was performed on all subjects. We simultan...

BACKGROUND Gastric cancer is a leading cause of cancer deaths worldwide but there are few data from Africa. We recently observed a trend towards diagnosis in younger patients. OBJECTIVE To test the hypothesis that HIV might have altered risk factors for acquisition of gastric cancer, in a case-control study in the University Teaching Hospital, Lusaka, Zambia. METHODS Patients (n=52) with co...

Copyright © 2017 JCBN 2017 This is an open access article distributed under the terms of the Creat ve Commons Attribution Licens , which permit unrest icted use, distribution, and reproduction i any medium, p o vided the original work is prop rly cit d. Recently here has been a n ticeable increas in th n ber f papers describing diagnosis and treatment of non-ampullary duodenal epithelial tumors...