E-cadherin is a tumor suppressor protein that plays a crucial role in cell-cell adherens junction and tissue architecture and it is hypothesized to participate in carcinogenesis. It has been shown that a polymorphism in the upstream of the transcription start site of the CDH1 gene affects E-cadherin transcriptional regulation and seems to be associated with a variety of cancers. For the first t...

Background: Gastric cancer patients usually suffer from skeletal muscle depletion. The serum creatinine/cystatin C ratio (CCR) is a new, simple tool that could serve as biomarker of mass. This study explored the ability preoperative CCR to predict postoperative complications in with gastric cancer.

Gastric Cancer (GC) is the fifth leading cancer in world and third cause of cancer-related death. The 5-year survival rate advanced gastric less than 30%, it very important to prevent cancer. Current methods are eradication H. pylori, early endoscopic diagnosis treatment. Chemoprevention using natural, synthetic, or biological substances prevent, reverse development cancer, thereby reducing inc...

ba ckground: although some studies have shown positive effects of omega-3 fatty acid supplementation on nutritional status of cancer patients undergoing different treatments, there is no consistency in results. the aim of this study was to examine the effects of omega-3 fatty acid on the nutritional status of gastric cancer patients during the course of chemotherapy. m ethods : in a double-blin...

abstract background: in iran gastric cancer is the second most common cancer and the most cause of death cancer, the aim of this study is provide map geographical distribution of gastric cancer and detect high risk cluster with use of space-time scan statistic. methods: this was an applied study. the data is provided from reports published by center for disease control office in ministry of hea...

objective her-2/neu gene is overexpressed in diverse human cancers and studies suggest a role of its product – p185 protein – in tumor progression by specifically promoting the invasive capacity of tumor cells. our aim was to evaluate her-2/neu content in resectable gastric cancer in this geographical region and assess the relationship between p185 expression and clinicopathologic tumor paramet...

objective: acorus calamus (a. calamus) has been used as a medicinal plant in asia for its effects on digestive system for the last 2000 years. to investigate the anti-cancer activity of rhizome of a. calamus, the ethanolic and methanolic extracts and essential oil of the rhizome were prepared and their effects were assessed on human gastric cancer cell line (ags). materials and methods: the via...

matrix metalloproteinases (mmps) play an important role in gastric cancer (gc). accumulated evidence suggests that functional mmp-1 and mmp-7 gene polymorphisms are associated with several tumors. the aim of this study was to investigate two single nucleotide polymorphisms, mmp-1 -1607 1g/2g and mmp-7 -181 a/g, and their potential relationship with gc. we examined 246 gc  patients and 252 age-a...

background : the aim of this study was to predict the survival rate of iranian gastric cancer patients using the cox proportional hazard and artificial neural network models as well as comparing the ability of these approaches in predicting the survival of these patients. methods: in this historical cohort study, the data gathered from 436 registered gastric cancer patients who have had surgery...