OBJECTIVE To evaluate the natural history of gastric emptying in diabetes. RESEARCH DESIGN AND METHODS Thirteen patients with diabetes (12, type 1; 1, type 2) had measurements of gastric emptying, blood glucose levels, glycated hemoglobin, upper gastrointestinal symptoms, and autonomic nerve function at baseline and after 24.7 ± 1.5 years. RESULTS There was no change in gastric emptying of ...

The traditional Japanese medicine rikkunshito ameliorates the nitric oxide-associated delay in gastric emptying. Whether rikkunshito affects gastric motility associated with 5-hydroxytryptamine (serotonin: 5-HT) receptors or dopamine receptors is unknown. We examined the effects of rikkunshito on the delay in gastric emptying induced by 5-HT or dopamine using the phenol red method in male Wista...

PURPOSE Gastric surgery may potentiate delayed gastric emptying. Billroth I gastroduodenostomy using a circular stapler is the most preferable reconstruction method. The purpose of this study is to analyze the risk factors associated with delayed gastric emptying after radical subtotal gastrectomy with Billroth I anastomosis using a stapler for early gastric cancer. METHODS Three hundred and ...

TO THE EDITOR: We read with great interest the report by Nonaka et al about the effects of histamine-2 receptor antagonists and proton pump inhibitors (PPIs) on gastric emptying. The authors clearly showed that a single intravenous injection of famotidine and omeprazole had no effects on gastric emptying using the continuous real-time C breath test (Breath ID System) in a randomized placebo-con...

A new scintigraphic measurement technique is described that allows accurate assessment of gastric emptying in between as well as during a number of successive meals. Measurements were made every minute of food intake, gastric nutrient filling, and gastric emptying over a 6 h, 40 min period in conscious, free-feeding, loosely restrained rats. Before receiving access to the food, the animals had ...

Direct as well as indirect evidence suggests that rapid gastric emptying may be occurring in Mexican Americans, American Indians, and other ethnic groups. Mexican Americans have been shown to have a more rapid rate of gastric emptying compared to non-Hispanic Whites after matching for weight, sex, and body mass index. Indirect evidence also suggests that American Indians and other ethnic groups...

TO THE EDITOR: I read the paper by Yu et al entitled “Gastric emptying in migraine: a comparison with functional dyspepsia.” The authors measured gastric emptying time in 27 patients with migraine, 32 patients with functional dyspepsia (FD) and 12 healthy controls in order to investigate whether delayed gastric emptying plays a pathogenic role in FD patients or migraine patients without any gas...

Gastric emptying was compared in patients with gastric cancers and fundal gastritis to determine its value in identifying patients at high risk of gastric cancer. Gastric emptying was measured by the acetaminophen absorption method, and the extent of fundal gastritis was determined by the endoscopic Congo red test. The results showed that gastric emptying was significantly slower in patients wi...

We investigated the effect of acarbose, an alpha-glucosidase and pancreatic alpha-amylase inhibitor, on gastric emptying of solid meals of varying nutrient composition and plasma responses of gut hormones. Gastric emptying was determined with scintigraphy in healthy subjects, and all studies were performed with and without 100 mg of acarbose, in random order, at least 1 wk apart. Acarbose did n...

Noninvasive imaging has been developed to measure gastric volumes. The relationship between gastric emptying and volume postprandially is unclear. The aims were to 1) develop a 3-dimensional (3D) single photon emission-computed tomography (SPECT) method to simultaneously measure gastric volume and emptying postprandially, 2) describe the course of gastric volume change during emptying of the me...