A mortality odds ratio (MOR) study has been conducted to explore the cancer risks of exposures experienced in the production of optical lenses and metal spectacle frames. Male death certificates were obtained from a Massachusetts town where a large optical industry is located. Craftsmen, foremen, and operatives of non-optical industries, such as woollen textile workers and workers in the optica...

Gastrointestinal (GI) cancer is one of the leading causes death that affect many patients around world. The coronavirus disease 2019 (COVID-19) pandemic significantly impacted our healthcare system in large diagnosis and management GI have suffered with a reduction screening. This review will describe current practices screening during COVID-19 summarize how each (esophageal, gastric, colorecta...

background : although, family history of cancer is an important risk factor for upper gastrointestinal cancers development, but limited information is available on the upper gastrointestinal cancers associated with family history in iran. the purpose of this study was to define upper gastrointestinal cancers risk associated with family history of cancer. methods : this study was conducted as a ...

approximately 20% of the incidence of cancers are caused by obesity. there have been several studies showing that weight loss, through calorie reduction and increased exercise, can potentially reduce the risk of cancer in obese people. but currently other special methods such as anti-obesity drugs or bariatric surgeries are used for intentional weight loss. whether such intentional weight loss ...

Early gastrointestinal cancers are defined as lesions limited to the mucosa or submucosa without invading the muscularis propria, regardless of the presence of lymph node metastases. Although the natural history of these diseases is basically alike worldwide, its management is quite different between the East and West; aggressive surgery is frequently adopted by Western surgeons, while less inv...

Previous studies reported that endoscopic resection is effective for the treatment of superficial pharyngeal cancers, as for digestive tract cancers. However, the optimal treatment for superficial cancer of the uvula has not been established because of the rarity of this condition. We present two male patients in their 70s with superficial cancer of the uvula, detected with upper gastrointestin...

Gastrointestinal neuroendocrine cancers are of significant interest to clinicians and basic scientists. Although accuracy of diagnosis has improved with advances in radioimmune and hormonal assays and in the diagnosis of earlier disease by computed tomography (CT) and magnetic resonance imaging (MRI), many patients still present with hepatic metastases. In contrast to most metastatic gastrointe...

Mutation frequencies at 25 genes containing coding repeats were compared in colorectal, gastric, and endometrial mismatch repair-deficient (MSI-H) tumors. The overall number of mutations was significantly lower in endometrial than in gastrointestinal MSI-H cancers. Using a likelihood statistical method, target genes were divided in each tumor location into two groups likely to represent gene mu...