background : the purpose of this study was to determine reliability and construct validity of a persian version of the gastrointestinal symptoms rating scale (gsrs) in 2 samples of patients with functional gastrointestinal disorders (fgid) and healthy persons. materials and methods : the clinical sample consisted of 143 patients diagnosed with fgid who were referred to the psychosomatic disorde...

OBJECTIVES To determine if a discrepancy exists between subjective symptoms and the grade of endoscopic gastroesophageal reflux disease (GERD) in diabetes mellitus (DM) patients. METHODS All 2,884 patients who underwent esophagogastroduodenoscopy completed the modified Gastrointestinal Symptom Rating Scale (GSRS), an interview-based rating scale consisting of 16 items including a question on ...

BACKGROUND This randomized double blind placebo controlled dual site clinical trial compared a probiotic dietary supplement to placebo regarding effects on gastrointestinal symptoms in adults with post-prandial intestinal gas-related symptoms (abdominal pain, distention, flatulence) but no gastrointestinal (GI) diagnoses to explain the symptoms. METHODS Sixty-one adults were enrolled (age 36....

BACKGROUND/AIMS Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function and self-perceived functional gastrointestinal symptoms in major depression. METHODS Patients with major depression (n = 73) and controls represe...

BACKGROUND Symptoms of dyspepsia significantly disrupt patients' lives and reliable methods of assessing symptom status are important for patient management. The aim of the current study was to document the psychometric characteristics of the Gastrointestinal Symptom Rating Scale (GSRS) and the Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD) in Afrikaans, German, Hungarian, Itali...

It is reported that a conversion from mycophenolate mofetil (MMF) to enteric-coated mycophenolate sodium (EC-MPS) relieves gastrointestinal (GI) symptom burden and improves health-related quality of life (HRQoL). However, it is unclear whether renal transplant recipients using tacrolimus receive the same benefit from the conversion. In this prospective, multi-center, open-label trial, patients ...

Objective: To explore the influence of peritonitis on CAPD patients of gastrointestinal symptoms and gastric myoelectrical activity, and to explore the correlation between gastrointestinal symptoms and gastric myoelectrical activity. Methods: 72 patients were selected, including 24 patients with suffering peritonitis (group A), 24 patients with having suffered and cured peritonitis 3 months ago...

BACKGROUND Symptoms of heartburn has an impact on health-related quality of life (HRQL). When a questionnaire is translated into a new language, a linguistic validation is necessary but not sufficient unless the psychometric characteristics have been verified. The aim is to document the psychometric characteristics of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) an...

Background: Irritable bowel syndrome is one of the most common functional disorders of the digestive tract which causes a lot of problems for patients. Medicinal plants may decrease symptoms and improve patients` life. Objective: The aim of this study is to investigate the effectiveness of ginger on the symptoms of IBS. Methods: In this triple blind clinical trial, 64 patients with irritable...

The aim of this study was to investigate whether consumption of probiotic fermented milk containing Bifidobacterium bifidum YIT 10347 improves symptoms in patients with functional gastrointestinal disorders (FGID). Thirty-seven FGID patients (18 male, 19 female) aged 12-80 years (mean ± SD, 52.6 ± 17.5 years) whose condition had not improved despite being seen at several medical institutions co...