We have previously demonstrated promising anticancer efficacy of orally-fed whole ginger extract (GE) in preclinical prostate models emphasizing the importance of preservation of the natural "milieu". Essentially, GE primarily includes active ginger phenolics viz., 6-gingerol (6G), 8-gingerol (8G), 10-gingerol (10G), and 6-shogaol (6S). However, the druglikeness properties of active GE phenolic...

The Ge(IV) chlorometallate complexes, [EMIM]2 [GeCl6 ], [EDMIM]2 [GeCl6 ] and [PYRR]2 [GeCl6 ] (EMIM=1-ethyl-3-methylimidazolium; EDMIM=2,3-dimethyl-1-ethylimidazolium; PYRR=N-butyl-N-methylpyrrolidinium) have been synthesised and fully characterised; the first two also by single-crystal X-ray diffraction. The imidazolium chlorometallates exhibited significant CH⋅⋅⋅Cl hydrogen bonds, resulting...

Recombination is thought to be an important source of genetic variation in herpesviruses. Several studies, performed in vitro or in vivo, detected recombinant viruses after the coinoculation of two distinguishable strains of the same herpesvirus species. However, none of these studies investigated the evolution of the relative proportions of parental versus recombinant progeny populations after...

A Ge67Cu33 (16 nm) layer and a Ge (3 nm)/Ge67Cu33 (16 nm) bilayer were grown by sputtering at room temperature and used as the recording films for write-once blue laser media. In comparison to the crystallization temperature of Ge in a GeCu film (380.7 °C-405.1 °C), the crystallization temperature of Ge in a Ge/GeCu bilayer could be further decreased to 333.7 °C-382.8 °C. The activation energie...

In this work the Monte Carlo method with an empirical potential model for atomic interactions is applied to study reconstruction and intermixing at a Ge-covered Si~001! surface. We investigate the structure and energetics of the 23n reconstruction which serves as a strain-relief mechanism. The optimal value of n is found to be strongly dependent on the thickness of the Ge overlayer. Si-Ge inter...

Let g be a classical Lie algebra, i.e., either gl n , sp n , or son and let e be a nilpotent element of g. We study various properties of centralisers ge. The first four sections deal with rather elementary questions, like the centre of ge, commuting varieties associatedwith ge, or centralisers of commuting pairs. The second half of the paper addresses problems related to different Poisson stru...

HYPOTHESIS Ginseng root extracts and the biologically active ginsenosides have been shown to inhibit proliferation of human cancer cell lines, including breast cancer. However, there are conflicting data that suggest that ginseng extracts (GEs) may or may not have estrogenic action, which might be contraindicated in individuals with estrogen-dependent cancers. The current study was designed to ...

Boron (B)-deficient pumpkin (Cucurbita moschata Duchesne) plants exhibit reduced growth, and their tissues are brittle. The leaf cell walls of these plants contain less than one-half the amount of borate cross-linked rhamnogalacturonan II (RG-II) dimer than normal plants. Supplying germanium (Ge), which has been reported to substitute for B, to B-deficient plants does not restore growth or redu...