abstractvarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (slns). due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. different strategies have been employed to overcome this problem. in this direction, the present study introduces erodible in-situ forming gel systems ...

preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles. nanoparticles (nps) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. to solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

Este trabalho consistiu na preparação e caracterização de microesferas quitosana (MQUI), quitosana/gelatina (MQUI/GEL), carregadas com cromo (MQUI-Cr MQUI/GEL-Cr) magnésio (MQUI-Mg MQUI-GEL-Mg). As foram preparadas pelo método emulsão reticulada utilizando o glutaraldeído como agente reticulação. O grau desacetilação (GD) da determinado por titulação potenciométrica foi 78,7%. espectro região d...