Atypical manifestation of Huntington's disease (HD) could inform ongoing research into HD genetic modifiers not present in the primarily European populations studied to date. This work demonstrates that expanding HD genetic testing into under-resourced healthcare settings can benefit both local communities and ongoing research into HD etiology and new therapies.

We describe N 2 VIS, an interactive visualization tool for feedforward neural network populations trained through evolutionary computation. N 2 VIS provides vi-sualization of network attributes including topology, connection weights, weight volatility, and nodal activation levels for speciic input values, as well as of genealogical relationships between diierent networks. Changes to network par...

We review and develop Bayesian statistical methods for recovering genealogical structure, population size and mutation rates from radiocarbon-dated fossil mtDNA sequence data. It is possible to obtain ages for fossil DNA sequences and their common ancestors, by fitting a population-genetic model. We describe the observation model and show how uncertainty in reconstructed parameter values may be...