probiotics, living microorganisms which when used in adequate amounts, have health benefits on the host, have attracted a considerable deal of interest in the biotechnology market. various prokaryotic and eukaryotic microbes have been studied for probiotic purposes in human and animals. lactobacillus and bifidobacterium are the main probiotic genera; however, there are reports on the probiotic p...

Food materials designated as "Generally Recognized as Safe" (GRAS) are attracting the attention of researchers in their attempts to systematically identify compounds with putative health-related benefits. In particular, there is currently a great deal of interest in exploring possible secondary benefits of flavor ingredients, such as those relating to health and wellness. One step in this direc...

The US Food and Drug Administration (FDA) has premarket review authority over food additives, but a food manufacturer may, according to the legislation, intentionally add a substance to human food or animal food without their premarket review or approval if the substance is generally recognized, among qualified experts, to be safe under the conditions of its intended use. Generally recognized a...

We, the undersigned, an independent panel of recognized experts (the Expert Panel), qualified by our scientific training and relevant national and international experience in evaluating the safety of food and food ingredients, were requested by the Health and Food Technologies business unit of Cargill, Incorporated (Cargill) to determine the safety and the Generally Recognized As Safe (GRAS) st...

n 1958, Congress enacted the Food Additives Amendment (FAA) to the Federal Food, Drug, and Cosmetics Act amid growing concern over the safety of substances added to foods. The FAA set forth standards and guidelines by which the safety of food additives must be established before they can be added to foods (FAA, 1958). The FAA contained an exclusion provided by Congress for substances “generally...

First, let me explain what GRAS means. GRAS is an acronym for "generally recognized as safe. " It refers to a large number of chemical compounds that the FDA considers to be safe when added to foods. The legal basis for GRAS status is rather complicated and goes back over many years to early federal regulations dealing with food additives. In 1958 the FDA solicited opinions from the scientific ...