a data file containing 607662 (317608) milk (open days) records belonging 294417 (177838) holstein cows that were calved from 1983 to 2008 was used. the bivariate repeatability model was used for data analyzing so that herd, calving year, calving month, days in milk (only for milk trait) and calving age for each parity, were assumed as fixed effects and additive genetics and permanent environme...

With the aim of estimating the coefficient of heritability of average annual productivity of Nellore cows (COWPROD), a data set from 24,855 animals with known pedigree was analyzed. COWPROD is defined as the amount (in kilograms) of weaned calves produced yearly by one cow during her remaining time in herd ignoring a fixed period of 365 days. COWPROD was calculated regarding three standards: a)...

Genetic association studies usually apply the simple chi-square (χ2)-test for testing between a single-nucleotide polymorphism (SNP) and particular phenotype, assuming genotypes phenotypes are independent. So, conventional χ2-test does not consider increased risk of an individual carrying increasing number disease responsible allele (a genotype). But, tests should be performed with consideratio...

National reference standards (NRSs) for biologics are established through potency estimation by a multicenter joint study of standard materials used in the approval process for national lot release and quality control of vaccines, blood products, and other biologics. In this study, a stability evaluation was conducted to determine whether the potency of NRSs for six blood products was being mai...

Genetic trend for milk yield in the artificially sired Holstein population in the northeastern United States was estimated from solutions for simultaneous genetic evaluations of bulls and cows for an animal model using mixed model equations and including all known relationships among the population by years of birth of 1960 to 1980 (1978 for bulls). First lactation milk records of 1,074,971 art...