Fissured tongue (lingua plicata; LP) is a mostly asymptomatic condition characterized by grooves and fissures of varying depth on the dorsal surface of the tongue. Most reports in the literature indicate a prevalence of 10–20%, although there is marked variation. On the basis of 1,000 patients (n=465 males, n=535 females), this study examined the association between LP and age as well as furthe...

It has often been remarked that bioethics is a quintessentially American phenomenon. Broadly speaking, bioethics as a field has tended to enshrine the value of autonomy, it places individual rights above communal well-being, and it has adopted a largely permissive and optimistic view of emerging biotechnologies. In contrast to much European thinking at the intersection of ethics and medicine, A...

OBJECTIVE The interest in the study of the tongue papillary niches and the related biofilm has increased in recent years because they form a suitable source of periodontal microorganisms and are associated with development of halitosis. Tongue dorsum structure represents a factor favoring a particular and complex bacterial biofilm where periodontal pathogens are frequently found. The aim of thi...

Primates in the laboratory often perform tasks that involve discrimination of pictures shown on computer screens. It is not clear, however, if they perceive the pictures as symbolic representations of real objects. In this study we tested the ability of two monkeys (Macaca mulatta) to categorize pictures on a computer screen. The pictures were photographs of objects from 17 categories, which we...

Age-related maculopathy (ARM) remains a poorly understood degeneration. To discover new pathways using contemporary genomics, proteomics, and immunohistochemistry, validate emerging animal models, and validate new imaging modalities, human tissues obtained from donor eyes will be essential to ARM research for the foreseeable future. Because fundus appearance is the clinical diagnostic lingua fr...

Biologists are increasingly recognising that computational modelling is crucial for making sense of the vast quantities of complex experimental data that are now being collected. The systems biology field needs agreed-upon information standards if models are to be shared, evaluated and developed cooperatively. Over the last four years, our team has been developing the Systems Biology Markup Lan...

Pendahuluan: Lidah dalam filosofi medis dipercaya sebagai barometer kesehatan rongga mulut maupun tubuh secara keseluruhan. Permukaan mukosa lidah kadang memperlihatkan gambaran yang berbeda dari kondisi normal sehingga disebut variasi normal. Geographic tongue dan fissured merupakan suatu asimptomatik namun dapat menjadi simptomatik ketika dipengaruhi kebiasaan baru bersifat mengiritasi sepert...

Abstract This is a case report of 27-year-old male who presented with recurrent facial swelling and weakness. The clinical evaluation revealed that the patient had Melkersson-Rosenthal syndrome (MRS), rare neurological disease characterized by triad edema, muscle weakness, furrowed or fissured tongue. Accurate data regarding incidence MRS challenging to obtain due rarity disorder, early recogni...

The lingual localization of an enteric duplication is extremely rare but may present with respiratory and feeding problems that require emergency intervention. A 7-month-old boy was brought to our clinic with feeding difficulties and tongue swelling. Physical examination showed a cystic lesion located near the left side of the tongue base that caused tongue protrusion to the contralateral side....

In March, 2010, a 53-year-old woman developed a black discolouration of her tongue. 4 weeks before developing the discolouration, she had had elective gynaecological surgery, from which she was recovering as an inpatient under our care. She did not smoke, but had a high intake of caff einated drinks, including six cups of tea and two cups of coff ee each day. During the course of her hospital s...