background: although heterotopic gestation is common in assisted reproductive techniques, it is very rare in natural conception and clomiphene induced pregnancy. diagnosis and appropriate intervention of heterotopic pregnancy requires a high index of suspicious. case: in this paper a case of heterotopic pregnancy in a 30-year old woman with hemoperitoneum from ruptured tubal pregnancy with live...

Gregarious mammals generally synchronize birthing by adjusting the time of estrus. Berger (Ecology 73: 323-329, 1992) proposed that American bison (Bison bison) females in good condition are capable of adjusting gestation length, as well. He hypothesized that females in good condition that breed late in the season can shorten their gestation length so as to give birth during the birthing peak. ...

We have investigated whether cortisol pretreatment of sheep fetuses will result in a greater liquid accumulation within the lung and a greater lung growth response to obstruction of the fetal trachea. Chronically catheterized fetal sheep received either 1) a cortisol infusion at an increasing dose (1.5-4.0 mg/day) from days 118 to 127 of gestation; the fetal trachea was then obstructed from day...

Congenital diaphragmatic hernia (CDH) may be an ideal candidate disease for in utero gene therapy as disrupted fetal lung growth plays a significant role in disease outcome. We previously demonstrated that transient in utero overexpression of CFTR during fetal development resulted in lung epithelial proliferation and differentiation. We hypothesized that gene therapy with CFTR would improve the...

BACKGROUND The purpose of this study was to compare the fetal/infant mortality risk associated with each additional week of expectant management to that associated with immediate delivery in women with multiple gestations. METHODS This was a retrospective national cohort study of 94,170 multiple deliveries, 92,619 (98.4%) twin and 1,352 (1.44%) triplet pregnancies, between 32 0/7 and 42 6/7 w...

OBJECTIVE To estimate the effect of reducing caffeine intake during pregnancy on birth weight and length of gestation. DESIGN Randomised double blind controlled trial. SETTING Denmark. PARTICIPANTS 1207 pregnant women drinking at least three cups of coffee a day, recruited before 20 weeks' gestation. INTERVENTIONS Caffeinated instant coffee (568 women) or decaffeinated instant coffee (6...

We previously reported decreases in blood-brain barrier permeability in the ovine fetus at 80% of gestation after antenatal corticosteroids and shown that permeability is not reduced in newborn lambs after postnatal corticosteroids. We now test the hypotheses that exogenous antenatal corticosteroids decrease blood-brain barrier permeability at 60% but not 90% of gestation in ovine fetuses and t...

Factors associated with incidence of mummified fetuses at 7, 9, 11, 13 and 15 wk of gestation were determined in a cross-sectional design involving 209 pregnant pigs. Percentage of observed mummies increased from 2.1 to 12.2% as gestation progressed. Incidence of mummies at 7 wk of gestation was not different between litters of nine fetuses or fewer and those of 10 fetuses or more. During the p...