OBJECTIVE GFR-prediction equations based upon cystatin C and creatinine have better diagnostic performance in estimating GFR than equations based upon only one of the two markers. The present work concerns in what way a comparison between separate estimations of GFR based upon cystatin C (eGFR(cystatin C)) or creatinine (eGFR(creatinine)) can be used to evaluate the diagnostic performance of a ...

BACKGROUND Cystatin C measurement has been proposed as a replacement for creatinine as a serum measure of glomerular filtration rate (GFR). It has also been suggested that GFR itself should be adjusted to the extracellular fluid volume (ECV) of a child rather than the body surface area (BSA). AIMS To assess the potential of cystatin C compared to serum creatinine in assessing GFR and to estab...

BACKGROUND Chronic kidney disease (CKD) has been increasingly shown to be a negative prognostic factor after liver transplantation (Ltx). Creatinine-based glomerular filtration rate (GFR) formulas are notoriously insensitive. In children, non-invasive determination of GFR by measurement of serum cystatin C is feasible and repeatedly correlated to the gold standards of GFR measurements. The aim ...

BACKGROUND The glomerular filtration rate (GFR) assesses the function of all nephrons, and the single-nephron GFR assesses the function of individual nephrons. How the single-nephron GFR relates to demographic and clinical characteristics and kidney-biopsy findings in humans is unknown. METHODS We identified 1388 living kidney donors at the Mayo Clinic and the Cleveland Clinic who underwent a...

26 The screening for chronic kidney diseases (CKD) patients with impaired GFR needs the 27 measurement of serum creatinine (SCr) or cystatin C (SCys). GFR can also be predicted from 28 SCr or SCys with different formulas. Aim of this study, performed in a group of CKD 29 patients with different levels of GFR, was to evaluate the possibility to select the patients with 30 a GFR < 90 mL/min/1.73 ...

objective: measurement of glomerular filtration rate (gfr) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. as extremely accurate methods of gfr measurement (i.e. inulin clearance) are expensive and time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the gfr measurement. here we have ...

A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the ...

Aim: The mortality and morbidity of COVID-19 disease are higher in patients with comorbidities. In this study, we staged chronic renal failure hospitalized the intensive care unit (ICU) aimed to evaluate process according stage failure.&#x0D; Material Method: medical records 249 followed Ankara City Hospital MH3 ICU were reviewed retrospectively. divided into three stages their estimated glomer...

BACKGROUND Angiotensin II (AII) mediates glomerular filtration rate (GFR) decline in animals with subtotal nephrectomy (Nx), but the mechanisms for increased AII activity are unknown. Because reduced GFR of Nx is associated with acid (H(+)) retention that increases kidney AII, AII-mediated GFR decline might be induced by H(+) retention. METHODS We measured GFR and kidney microdialyzate H(+) a...

The ability of the Modification of Renal Disease (MDRD) equation to predict GFR when compared with multiple other prediction equations in healthy subjects without known kidney disease was analyzed. Between May 1995 and December 2001, a total of 117 healthy individuals underwent (125)I-iothalamate or (99m)Tc-diethylenetriamine-pentaacetic acid (DTPA) renal studies as part of a routine kidney don...