Both mandibular advancement (MA) and stimulation of the genioglossus (GG) have been shown to improve upper airway patency, but neither one achieves the effect of continuous positive airway pressure (CPAP) treatment. In the present study we assessed the combined effect of MA and GG stimulation on the relaxed pharynx in patients with obstructive sleep apnea (OSA). We evaluated responses of upper ...

The effects of sleep on the ventilatory responses to hypercapnia have been well described in animals and humans. In contrast, there is little information for genioglossus (GG) responses to a range of CO2 stimuli across all sleep-wake states. Given the notion that sleep, especially rapid-eye-movement (REM) sleep, may cause greater suppression of muscles with both respiratory and non-respiratory ...

Alarm pheromones (APs) are widely used throughout the plant and animal kingdoms. Species such as fish, insects, and mammals signal danger to conspecifics by releasing volatile alarm molecules. Thus far, neither the chemicals, their bodily source, nor the sensory system involved in their detection have been isolated or identified in mammals. We found that APs are recognized by the Grueneberg gan...

Low back pain is one of the most reported medical conditions associated to intervertebral disc (IVD) degeneration. Nucleus pulposus (NP) is often regarded as the structure where IVD degeneration begins. Gellan gum (GG)-based hydrogels for acellular and cellular tissue engineering strategies have been developed for finding applications as NP substitutes. The innovative strategy is based on the r...

in this paper, we propose a new method for fuzzy numbers. in this method, we assume that ai= (ai1, ai2, ai3, ai4) is to be a fuzzy number. so, the convex combination of ai1 and ai2 and also the convex combination of ai3 and ai4 are obtained separately. then, mic and mis that are to be the convex combinations and the standard deviation respectively we acquire them from these components. finally,...

The cyanobacterium Synechocystis sp. PCC 6803 accumulates the compatible solute glucosylglycerol (GG) and sucrose under salt stress. Although the molecular mechanisms for GG synthesis including regulation of the GG-phosphate synthase (ggpS) gene, which encodes GgpS, has been intensively investigated, the role of GG in protection against salt stress remains poorly understood. In our study of the...

AIM To estimate the association of vascular endothelial growth factor A (VEGFA) +936C/T and -634G/C polymorphisms and gastric cancer (GC) risk, a meta-analysis was performed. A total of nine studies were identified with 2,281 GC cases and 2,820 controls. This meta-analysis indicated significant associations between the VEGFA -634G/C polymorphism and GC risk were found for GC versus GG (OR 1.21,...

Mungbean (Vigna radiata) is an important short-season legume widely cultivated in Asia, particularly India. It highly susceptible to bruchids and developing bruchid resistance goal mungbean breeding programs. In the present study, 52 genotypes were evaluated for based on “no-choice test” identified two resistant (V2802BG V2709) with no adult emergence seed damage. Further, these crossed six hig...

We investigate the statistics of convex hull for a single run-and-tumble particle in two dimensions. Run-and-tumble particle, also known as persistent random walker, has gained significant interest recent years due to its biological application modelling motion bacteria. consider different statistical ensembles depending on whether (i) total number tumbles $n$ or (ii) observation time $t$ is ke...