Abstract. In this paper we propose a malaria within-host model with k classes of age for the parasitized red blood cells and n strains for the parasite. We provide a global analysis for this model. A competitive exclusion principle holds. If R0, the basic reproduction number, satisfies R0 ≤ 1, then the disease-free equilibrium is globally asymptotically stable. On the contrary if R0 > 1, then g...

In this paper, we formulate an SIR epidemic model with hybrid of multigroup and patch structures, which can be regarded as a model for the geographical spread of infectious diseases or a multi-group model with perturbation. We show that if a threshold value, which corresponds to the well-known basic reproduction number R0, is less than or equal to unity, then the disease-free equilibrium of the...

We present a stability criterion for switched nonlinear systems which involves Lie brackets of the individual vector fields but does not require that these vector fields commute. A special case of the main result says that a switched system generated by a pair of globally asymptotically stable nonlinear vector fields whose third-order Lie brackets vanish is globally uniformly asymptotically sta...

In this paper, a model for the use of heroin with treat-age is formulated based on the principles of mathematical epidemiology. The model accounts for relapse rate that depends on how long the host has been in treatment for heroin addiction. An explicit formula for the reproductive number of the heroin spread is obtained. By using the method of Lyapunov functional, we established the dynamical ...

The dynamics of an in-host model with general form of target-cell dynamics, nonlinear incidence, and distributed delay are investigated. The model can describe the in vivo infection dynamics of many viruses such as HIV-I, HCV, and HBV. We derive the basic reproduction number R0 for the viral infection and establish that the global dynamics are completely determined by the values of R0: if R0 ≤ ...

This paper deals with a delayed three-level food chain model with Beddington-DeAngelis functional response. By using the differential inequality theory, a set of sufficient conditions are obtained for the permanence of the system. By constructing a suitable Liapunov function, we derive that the system has a unique asymptotically periodic solution which is globally asymptotically stable. An exam...

The joint problem of the recursive estimation of an optimal predictor for the closed-loop system and the unbiased parameter estimation of an ARMAX plant model in closed-loop operation is considered. A special reparameterized optimal predictor for the closed-loop is introduced. This allows a parameter estimation algorithm for the plant model to be derived which is globally asymptotically stable ...

This paper studies monotone tridiagonal systems with negative feedback. These systems possess the Poincaré-Bendixson property, which implies that, if orbits are bounded, if there is a unique steady state and this unique steady state is asymptotically stable, and if one can rule out periodic orbits, then the steady state is globally asymptotically stable. Two different approaches are discussed t...

Abstract. In this paper, a predator-prey system with Holling type II functional response and stage structure is investigated. By analyzing the corresponding characteristic equations, the local stability of each of feasible equilibria of the system is studied. The existence of the orbitally asymptotically stable periodic solution is established. By using suitable Lyapunov functions and the LaSal...

We investigate the stability of mixed strategy equilibria in 2 person (bimatrix) games under perturbed best response dynamics. A mixed equilibrium is asymptotically stable under all such dynamics if and only if the game is linearly equivalent to a zero sum game. In this case, the mixed equilibrium is also globally asymptotically stable. Global convergence to the set of perturbed equilibria is s...