In this paper, we investigate global dynamics for a system of delay differential equations which describes a virus-immune interaction in vivo. The model has two distributed time delays describing time needed for infection of cell and virus replication. Our model admits three possible equilibria, an uninfected equilibrium and infected equilibrium with or without immune response depending on the ...

We use feedback control methods to prove existence of globally asymptotically stable equilibria for nonlinear (density dependent) population dynamics. We focus on populations modelled in discrete size or stage classes so that the model has a natural state space of nonnegative vectors in R. Combining comparison results and small gain techniques, we characterize the situations when there is a pos...

This paper investigates the global stability of virus dynamics model with BeddingtonDeAngelis infection rate. By constructing Lyapunov functions, the global properties have been analyzed. If the basic reproductive ratio of the virus is less than or equal to one, the uninfected steady state is globally asymptotically stable. If the basic reproductive ratio of the virus is more than one, the infe...

‎Hepatitis B virus (HBV) infection is a major public health problem in the world today‎. ‎A mathematical model is formulated to describe the spread of hepatitis B‎, ‎which can be controlled by vaccination as well as treatment‎. ‎We study the dynamical behavior of the system with fixed control for both vaccination and treatment‎. ‎The results shows that the dynamics of the model is completely de...

Abstract: This study is carried out to describe the behaviour of vehicles flow on the road, in the presence of blocking effects. A non-linear three dimensional system of ordinary differential equations is used to describe vehicles flow on the road. The study classify total vehicles population on the road into three compartments as Free – Slow – Released vehicles. The formulated model is well-po...

This note examines stability properties of systems that result from switching among globally asymptotically stable nonlinear systems in triangular form. We show by means of a counterexample that, unlike in the linear case, such a switched system might not be globally asymptotically stable, uniformly over all switching signals. We then formulate conditions that guarantee this uniform global asym...

An epidemic model with incomplete treatment and vaccination for the newborns and susceptibles is constructed. We establish that the global dynamics are completely determined by the basic reproduction number R0. If R0 ≤ 1, then the disease-free equilibrium is globally asymptotically stable. If R0 > 1, the endemic equilibrium is globally asymptotically stable. Some numerical simulations are also ...

In this paper, a HTLV-I infection model with CTL response is considered. To account for a series of events in infection process, we incorporate a intracellular time delay in the model. We prove that the global dynamics are determined by two threshold parameters R0 and R1, basic reproduction numbers for viral infection and for CTL response, respectively. If R0 < 1, the infection-free equilibrium...