Background: Different aspects of acute stroke management and strategies for stroke prevention derive from two viewpoints: specific traditional and historical backgrounds and evidence-based medicine from modern randomized controlled trials (RCTs), meta-analysis and authorized clinical practice guidelines (GLs). Regarding stroke, GLs have been published by national and international organizations...

We study the classical problem of the existence of irreducible plane curves with given degree d and prescribed singularities of topological types S1 ; : : : ; Sr. Our main results concern substantial improvements of the leading coeecients in the asymptotically optimal suucient conditions for complex plane curves which were found in GLS1]. We then transfer these results to real plane curves.

We have been developing a methodology/system called GLS (Global Learning Scheme) for knowledge discovery in databases. The development of GLS has two main aspects. The first is to develop a m&i-strategy system. That is, many kinds of discovery/learning methods are cooperatively used in multiple learning phases for performing multi-aspect intelligent data analysis as well as multi-level conceptu...

BACKGROUND Global longitudinal strain (GLS) is prognostic of adverse cardiovascular outcomes in various patient populations, but the prognostic utility of GLS for long-term cardiovascular morbidity and mortality in the general population is unknown. METHODS AND RESULTS A total of 1296 participants in a general population study underwent a health examination, including echocardiography measure...

BACKGROUND The management of patients with asymptomatic severe aortic stenosis (ASAS) is still under discussion. Therefore, it is advisable to search for the parameters of early damage to left ventricular (LV) function. AIM The aim of the study was to assess exercise-induced changes in LV global longitudinal strain (GLS) in ASAS. METHODS The ASAS group consisted of 50 patients (26 women and...

BACKGROUND Techniques of 2-dimensional speckle tracking enable the measurement of myocardial deformation (strain) during systole. Recent clinical studies explored the prognostic role of left ventricular global longitudinal strain (GLS). However, there are few data on the association between cardiovascular outcome and GLS in the community. Therefore, we hypothesized that GLS contains additive pr...

OBJECTIVES The purpose of this study was to investigate the prognostic value of global longitudinal strain (GLS) in heart failure with reduced ejection fraction (HFrEF) patients in relation to all-cause mortality. BACKGROUND Measurement of myocardial deformation by 2-dimensional speckle tracking echocardiography, specifically GLS, may be superior to conventional echocardiographic parameters, ...

This study aimed to test the ability of real-time three-dimensional echocardiography (RT3DE) to characterize early abnormalities of right ventricular (RV) structure and function with preserved left ventricular (LV) ejection fraction (EF) in uremic patients undergoing peritoneal dialysis (PD). Sixty-six uremic patients with preserved left ventricular ejection fraction (> 50% LVEF) undergoing per...

We investigated whether dendritic cells (DCs) play a role in favoring granular lymphocyte (GL) proliferation in patients with lymphoproliferative disease of granular lymphocytes (LDGL). The presence of in vivo circulating DCs was studied in 11 patients (5 CD3+ and 6 CD3- LDGL). Autologous immature (iDCs) and mature (mDCs) DCs generated in vitro were studied for stimulatory activity on cell prol...

Generalized least squares (GLS) regional regression procedures have been developed for estimating river flow quantiles. A widely used GLS procedure employs a simplified model error structure and average covariances when constructing an approximate residual error covariance matrix. This paper compares that GLS estimator (b̂GLS MC ), an idealized GLS estimator (b̂GLS E ) based on the simplifying as...