Glutathione is generally accepted as the principal electron donor for dehydroascorbate (DHA) reduction. Moreover, both glutathione and DHA affect cell cycle progression in plant cells. But other mechanisms for DHA reduction have been proposed. To investigate the connection between DHA and glutathione, we have evaluated cellular ascorbate and glutathione concentrations and their redox status aft...

BACKGROUND Tripeptide glutathione (gamma-glutamyl-L-cysteinyl-glycine) is the most abundant non-protein thiol that protects cells from metabolic and oxidative stresses and is widely used as medicine, food additives and in cosmetic industry. The methylotrophic yeast Hansenula polymorpha is regarded as a rich source of glutathione due to the role of this thiol in detoxifications of key intermedia...

The biological system of the microbial antioxidant protection is a subject certain level physiological oxidative process. To prevent oxidation, regulator intracellular metabolism, tripeptide glutathione, accumulated in cells. Glutathione very important for response and maintenance redox potential. Its role several metabolic adaptive symbiotic processes yeasts lactic acid bacteria not completely...

A simple and accurate quantitative assay of the glutathione-activated feeding reflex in Hydra is described. The results show: (a) There are a limited number of receptor-effector systems, probably localized in the area immediately around the mouth and on the tentacles. (b) Concentrations of glutathione greater than 5 x 10(-6)M activate all these systems; 10(-5)M glutathione elicits a half-maximu...