the present study investigates the antioxidant potential of the ethyl acetate fraction of the aerial parts eclipta alba l. hassk (eaea) which was widely used as hepatoprotective plant. eaea was orally administered at doses of 50, 100 and 200 mg/kg for 7 days in male charles foster rats. the extent of hepatoprotective potential of e . alba was studied by assessing the biochemical parameters like...

effects of pongamia pinnata, an indigenous plant used in ayurvedic medicine in india on the temporal variations of circulatory lipid peroxidation products and antioxidants in ammonium chloride-(ac)-induced hyperammonemic rats has been studied. experimental rats were divided into control, ac-treated, those treated with ac + ethanolic leaf extract of p. pinnata (ppet), and ppet-treated. the chara...

Chilling whole rice seedlings at 5 degrees C significantly increased the time needed to recover linear growth and reduced the subsequent linear rate of radicle growth. Subjecting nonchilled seedlings to a 45 degrees C heat shock for up to 20 min did not alter subsequent growth, whereas a 3 min heat shock was optimal in reducing growth inhibition caused by 2 days of chilling. The activity of fiv...

Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotoci...

In diabetic patients, persistence of hyperglycemia has been reported as a cause of increased production of oxygen free radicals. Hyperglycemia could induce oxidative stress and become the main factor for predisposing the complications in diabetes. The study is being aimed to find out the status of lipid peroxidation product i.e. malondialdehyde (MDA) and antioxidant enzymes (AOEs) such as gluta...

The activity of glutathione peroxidase (GPx), glutathione reductase (GR) and glutathione S-transferase (GST) was investigated in liver and kidney of rats exposed to cadmium (Cd) and ethanol (EtOH) alone and in combination. Rats were treated with 50 mg Cd/dm3 in drinking water and/or 5 g of EtOH/kg body wt/24 h intragastrically, for 12 weeks. Exposure to Cd led to an increase in GPx and GST acti...

Although its concentration is generally not known, glutathione peroxidase-1 (GPx-1) is a key enzyme in the removal of hydrogen peroxide (H2O2) in biological systems. Extrapolating from kinetic results obtained in vitro using dilute, homogenous buffered solutions, it is generally accepted that the rate of elimination of H2O2 in vivo by GPx is independent of glutathione concentration (GSH). To ex...

Ethanolic extract (50 %) of stems of Calotropis gigantea R. Br. (Asclepiadaceae) at doses of 250 and 500 mg kg-1 were studied for hepatoprotective activity in male Wistar rats with liver damage induced using carbon tetrachloride, 2 mL kg-1 twice a week. The protective effect of C. gigantea extract was compared with the standard drug silymarin. Various biochemical parameters such as aspartate am...

The experiment was conducted to study the effect of different dietary supplementation alanyl-glutamine dipeptide (AGD) and/or vitamin E (VE) on growth performance, antioxidant indexes, and expression glutathione peroxidase (GPx) peroxisome proliferator-activated receptor α (PPARⱭ) genes in juvenile marine medaka (Oryzias melastigma) seawater acidification. Seven groups triplicate were studied a...