BACKGROUND Oxidative stress constitutes the basis for many diseases and it may account for the severity of systemic and oral disease complications. The aim of this study was to assess whether saliva may be used to detect the body's oxidative stress level. METHODS Oxidative stress was determined in saliva from 14 diabetic patients and 10 heroin addicts; two different pathologic conditions rela...

objective: today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-zro2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. however, there are some reports implying that use of nano-zro2 is associated with cytotoxic effects like inhibiting the cell proliferation, dna damage and apoptosis. in the present study, we examined whether nano-z...

We investigated alterations in the ageing-related parameters: multiple-unit action potentials, Na(+), K(+)-ATPase activity, glutathione-s-transferase (GST) activity, glutathione peroxidase (GPx) activity, lipid peroxidation and lipofuscin contents in the brain regions cerebral cortex, striatum, hippocampus and thalamus, resulting from the chronic administration of aluminium chloride (AlCl3) in ...

This study investigates the effect of oral administration of an aqueous Enicostemma littorale whole plant extract on antioxidant defense in alloxan-induced diabetes in rats. A significant increase in blood glucose and increased concentration of thiobarbituric acid reactive substances (TBARS) and hydroperoxides (HP) in liver, kidney and pancreas were observed in alloxan diabetic rats. Decreased ...

Probiotics have been found as important elements against reproductive toxicity. So the use of probiotics has increased day by to combat with several disorders related health. In current study, potential role including Lactobacillus casei (L1) and coagulans (L2) demonstrated a tetramic acid-derived pesticide Spirotetramat which cause variable toxicity at different levels in life cycle various or...

The present study investigates the antioxidant potential of the ethyl acetate fraction of the aerial parts Eclipta alba L. Hassk (EAEA) which was widely used as hepatoprotective plant. EAEA was orally administered at doses of 50, 100 and 200 mg/kg for 7 days in male Charles Foster rats. The extent of hepatoprotective potential of E . alba was studied by assessing the biochemical para...

Effects of Pongamia pinnata, an indigenous plant used in Ayurvedic Medicine in India on the temporal variations of circulatory lipid peroxidation products and antioxidants in ammonium chloride-(AC)-induced hyperammonemic rats has been studied. Experimental rats were divided into control, AC-treated, those treated with AC + ethanolic leaf extract of P. pinnata (PPEt), and PPEt-treated. The...

This study was aimed to examine the protective effects of supplementation with calcium + zinc (Ca + Zn) or vitamin E (Vit-E) on Cd-induced renal oxidative damage. Young albino Wistar rats (180 ± 10 g) (n = 6) control rats, Cd, Cd + Ca + Zn, and Cd + Vit-E experimental groups and the experimental period was 30 days. Rats were exposed to Cd (20 mg/kg body weight) alone treated as Cd treated group...

Psoriasis is one of the skin’s chronic inflammatory diseases. etiology isn’t exactly known. Recently, it has been suggested that imbalances in oxidant-antioxidant status happening because increase reactive oxygen species production (ROS) and/or deficient function regarding antioxidant system might be included psoriasis pathogenesis. The major goal to evaluate defense patients experiencing and o...

Various pharmacological effects including anti-inflammatory and anti-oxidant properties were shown for woody endocarpium of walnut alcoholic extract (WEW). In the study, effect WEW in acetic acid induced ulcerative colitis rats was evaluated. Thiol, glutathione peroxidase (GPX), malondialdehyde (MDA), superoxide dismutase (SOD) gastric levels pathological changes colon investigated control grou...