A halotolerant cyanobacterium Aphanothece halophytica thrives in extreme salinity with accumulation of a potent osmoprotectant glycine betaine. Recently, this cyanobacterium was shown to accumulate sunscreen molecule mycosporine-2-glycine significantly at high salinity. In this study, we investigated effects of nitrate and amino acid provision on the accumulation of glycine betaine and mycospor...

The rates of conversion of glycine into serine and serine into glycine have been determined by administration of isotopically labelled glycine and serine (Arnstein & Neuberger, 1953; Elwyn & Sprinson, 1954; Arnstein & Keglevi6, 1956; Arnstein & Stankovid, 1956). The present investigation, which is concerned with the net synthesis of glycine from serine, and of serine from glycine, was carried o...

a stable agrobacterium-mediated transformation system was established using bialaphos as the selective agent in soybeans [glycine max (l.) merr.]. the cotyledonary node explants of the soybean cultivar ‘ny-1001’ were inoculated with the agrobacterium tumefaciens strain eha105, harboring the vector pcambia3301 containing the gus gene as the reporter gene and the bar gene conferring bialaphos res...

Wixom et al. (1) reported that supplementation of the diet with aminoethanol equivalent to 1.5% glycine increased the grouTth of chicks on a glycine-deficient 35% casein diet to the same extent as did supplementation with glycine. Such a magnitude of growth response implies an efficient conversion of aminoethanol to glycine. However, with the use of a 20 $& casein ration we were unable to obtai...

Threonine oxidation to glycine was investigated in vivo in twelve growing pigs (27.4 kg live weight) fed on one of the following three diets with graded levels of threonine supply: a low-threonine diet (LT), a control well-balanced diet (C) or a high-threonine diet (HT), during 10 h constant infusion of L-[1-13C]threonine and [2-3H]glycine in the cranial vena cava and [1-14C]glycine in the port...

conclusions since most of the symptoms of metabolic diseases in newborns are same as the signs of sepsis or other common diseases of this period, and also early diagnosis and treatment of these illnesses, especially in diseases such as hyperglycemia, can be influential in neural function of babies, it calls for serious attention and clinical vision of the doctors to stop mortality caused by suc...

Ionotropic activation of NMDA receptors (NMDARs) requires agonist glutamate and co-agonist glycine. Here we show that glycine enhances the activation of cell survival-promoting kinase Akt in cultured cortical neurons in which both the channel activity of NMDARs and the glycine receptors are pre-inhibited. The effect of glycine is reduced by shRNA-mediated knockdown of GluN2A subunit-containing ...

Previously, it was shown that glycine prevented increases in intracellular calcium ([Ca2+]i) in Kupffer cells. Since Kupffer cells and T lymphocytes are derived from the same pluripotent stem cell, it was hypothesized that glycine would prevent increases in [Ca2+]i in lymphocytes and inhibit cell proliferation. Lymphocyte proliferation was measured in one-way MLC with spleen cells from DA and L...