Whole cell voltage-clamp electrophysiology was used to examine interactions between GABA and glycine at inhibitory amino acid receptors on rat olfactory bulb neurons in primary culture. Membrane currents evoked by GABA and glycine were selectively inhibited by low concentrations of bicuculline and strychnine, respectively, suggesting that they activate pharmacologically distinct receptors. Howe...

Although all bipolar cells in the retina probably use the excitatory transmitter glutamate, approximately half of the cone bipolar cells also contain elevated levels of the inhibitory transmitter glycine. Some types of cone bipolar cells make heterologous gap junctions with rod amacrine cells, which contain elevated levels of glycine, leading to the hypothesis that the bipolar cells obtain thei...

High-affinity glycine transport in neurons and glial cells is a primary means of inactivating synaptic glycine. We have synthesized a potent selective inhibitor of glycine transporter 1 (GlyT1), and characterized its activity using a quail fibroblast cell line (QT6). The glycine transporters GlyT1A, GlyT1B, GlyT1C, and GlyT2 were stably expressed in QT6 cells. The transporters expressed in thes...

Abstract In this study, we presented two reliable methods, the sol–gel and autocombustion, to synthesis a high purity BiFeO 3 single phase with low calcination time using glycine as chelating agent. The glycine-autocombustion method produced either or concentrations of reactants (Bi(NO ) + Fe(NO ), while glycine-sol–gel delivered reactants. case tartaric acid urea agents, mixtures Bi 25 FeO 40 ...

Abstract The hydrothermal liquefaction (HTL) of biomass is a strategic process to convert wet and waste feedstocks into liquid biofuel. In this work, we investigated the glucose glycine, alone together, mimic composition low-lipid content biomass. Experimental tests were performed in batch setup temperature range 200–350 °C. As feeding changed, distribution among different phases (gas, solid, b...

drought, as an abiotic stress inflicts destructive and harmful effects on plants at their different growth stages. plants react differently to drought. among their reactions is the production of such osmolytes as proline and glycine betaine. it seems that, through exogenous application of these materials, plant resistance to drought stress can be increased. therefore, a factorial experiment, ba...

Free glycine is known to have vital functions in the mammalian brain, where it serves mainly as both neurotransmitter and neuromodulator. Despite its importance, little is known about the metabolic pathways of glycine synthesis and degradation in the central nervous system. In this study, the pathway of glycine metabolism in astroglia-rich primary cultures from rat brain was examined. The cells...

1. Total RNA isolated from embryonic chick paravertebral sympathetic ganglia was used in a reverse transcription-polymerase chain reaction (RT-PCR) assay with a pair of degenerate oligonucleotide primers deduced from conserved regions of mammalian glycine receptor alpha-subunits. Three classes of cDNA were identified which encode portions of the chicken homologues of the mammalian glycine recep...

Seven lines of haploid Nicotiana tabacum tissue culture selected for resistance to normally toxic levels of the glycine analog glycine hydroxamate, a competitive inhibitor of the glycine decarboxylase reaction, were investigated. The presence of glycine hydroxamate greatly increased the intracellular concentration of both glycine and alanine in wild type and resistant cell lines, suggesting tha...