It has long been recognized that the modification of penicillin-binding proteins (PBPs) to reduce their affinity for beta-lactams is an important mechanism (target modification) by which Gram-positive cocci acquire antibiotic resistance. Among Gram-negative rods (GNR), however, this mechanism has been considered unusual, and restricted to clinically irrelevant laboratory mutants for most specie...

Gold nanorods are a promising nanoscale material in clinical diagnosis and treatment. The physicochemical properties of GNRs, including size, shape and surface features, are crucial factors affecting their cytotoxicity. In this study, we investigated the effects of different aspect ratios and surface modifications on the cytotoxicity and cellular uptake of GNRs in cultured cells and in mice. Th...

Carbon nanotubes (CNTs) act as efficient nanoreactors, templating the assembly of sulfur-terminated graphene nanoribbons (S-GNRs) with different sizes, structures, and conformations. Spontaneous formation of nanoribbons from small sulfur-containing molecules is efficiently triggered by heat treatment or by an 80 keV electron beam. S-GNRs form readily in CNTs with internal diameters between 1 an...

We have used molecular dynamics to calculate the thermal conductivity of symmetric and asymmetric graphene nanoribbons (GNRs) of several nanometers in size (up to approximately 4 nm wide and approximately 10 nm long). For symmetric nanoribbons, the calculated thermal conductivity (e.g., approximately 2000 W/m-K at 400 K for a 1.5 nm x 5.7 nm zigzag GNR) is on the similar order of magnitude of t...

We investigate the optical response of graphene nanoribbons (GNRs) using broadband nonlinear generation and detection capabilities nanoscale junctions created at LaAlO3/SrTiO3 interface. GNR nanoclusters measured to be as small 1–2 GNRs in size are deposited on LaAlO3 surface with an atomic force microscope tip. Time-resolved probes reveal a strong, gate-tunable second third harmonic response, ...

Graphene is a thin-film carbon material that has immense potential as key ingredient in new nanoelectronic and nanophotonic devices due to its unique characteristics. In particular, plasmons graphene appear practical tool for the manipulation of light with applications from cancer treatment solar cells. A motivating tunability properties been observed nanoribbons (GNRs) their geometrically cont...

This article analyzes the impact that sex of law enforcement officers might have on way they intervene in Intimate Partner Violence (IPV) situations, and if is determined by prejudices related to traditional gender roles within intimate relationships. A questionnaire was applied 1,872 GNR (Republican National Guard), Portugal. The results show differences beliefs perceptions subsequent decision...