GABAergic interneurons critically regulate cortical computation through exquisite spatiotemporal control over excitatory networks. Precision of this inhibitory control requires a remarkable diversity within interneuron populations that is largely specified during embryogenesis. Although interneurons expressing the neuronal isoform of nitric oxide synthase (nNOS) constitute the largest hippocamp...

Compared to the nerve guidance conduits (NGCs) constructed from a single layer of aligned nanofibers, bilayer NGCs with random and aligned nanofibers in the outer and inner layers are more robust and tear-resistant during surgical procedures thanks to an isotropic mechanical property provided by the random nanofibers. However, it remains unclear whether the random nanofibers will interfere with...

The NGCS is based on neuroscience research. While previous gesture classification systems were developed on the basis of gesture observation and their categories were heuristical, the NGCS links the phenomenology to the neurobiology of gestures. The theoretical assumption behind the NGCS is that its main kinetic and functional gesture categories are differentially associated with specific cogni...

The compressive mechanical properties of uniform and density-graded Al-6061 foams, produced by replication of polymer foams, are measured. hile the uniform foam shows compressive behavior characteristic of conventional (uniform) metallic foams with a near constant plateau stress, he density-graded foam exhibits a smoothly rising plateau stress. This behavior is modeled using a simple series com...

A semi-analytical method is used to study the effects of the multi vibration absorbers on the nonlinear functionally graded (FG) Euler-Bernoulli beam subjected to periodic load. The material properties of the beam are assumed to be continuously graded in the thickness direction. The governing equations of functionally graded beam are obtained based on the Hamilton's principle and these equation...

In this paper, dynamic modeling of a double layer cylindrical functionally graded (FG) microshell is considered. Modeling is based on the first-order shear deformation theory (FSDT), and the equations of motion are derived using the Hamilton's principle. It assumes that functionally graded length scale parameter changes along the thickness. Generalized differential quadrature method (GDQM) is u...

functionally graded aluminium/zirconia metal matrix composite was fabricated using stir casting technique followed by horizontal centrifugal casting process and a hollow cylindrical functionally graded composite (150 x 150 x 16 mm) was obtained with centrifuging speed of 1200 rpm. the microstructural evaluation and hardness test was carried out on the outer and inner surface of the functionally...

in this study, the vibration behavior of functional graded (fg) circular and annular nanoplate embedded in a visco-pasternak foundation and coupled with temperature change is studied. the effect of in-plane pre-load and temperature change are investigated on the vibration frequencies of fg circular and annular nanoplate. to obtain the vibration frequencies of the fg circular and annular nanopla...