BACKGROUND The aim of the present study was to assess semi-quantification of myocardial perfusion using adenosine triphosphate (ATP)-stress myocardial perfusion computed tomography (MPCT) in patients with coronary artery disease (CAD). METHODS AND RESULTS Seventeen patients with CAD underwent ATP-stress MPCT, stress myocardial perfusion scintigraphy (MPS) and coronary angiography (CAG). With ...

In a continuously stressful environment, the effects of recurrent prenatal stress (PS) may accumulate across generations and alter stress vulnerability and resilience. Here, we report in female rats that a family history of recurrent ancestral PS facilitates certain aspects of movement performance, and that these benefits are abolished by the experience of a second hit, induced by a silent isch...

A model was used to investigate stresses and deflections in cement bases and in a composite restorative material induced in a posterior Class I restoration. Deflections in the composite were highest when it was supported by a base with a low modulus; however, the maximum tensile stress (12 MN/meter2) occurring in the composite restoration at the interface with the base was well below the maximu...

Nerve guidance conduits (NGCs) are used as an alternative to the “gold standard” nerve autografting, preventing need for surgical intervention required harvest autologous nerves. However, regeneration outcomes achieved with current NGCs only comparable autografting when gap is short (less than 10 mm). In present study, we have developed made from a blend of polyhydroxyalkanoates, family natural...

OBJECTIVE To confirm that subtle changes in motor function and reaction time are present in presymptomatic individuals carrying the expanded Huntington disease (HD) allele. DESIGN A case-control, double-blind study comparing presymptomatic HD gene carriers (PSGCs) and nongene carriers (NGCs) at risk for HD. SETTING The Department of Medical and Molecular Genetics at a general clinical resea...

In this study, stress distributions on dental implants made of functionally graded biomaterials (FGBM) are investigated numerically. The implant body is considered to be subjected to axial compression loads. Numerical problem is assumed to be 2D, and ANSYS commercial software is used for the analysis. The cross section of the implant thread varies as varying the height (H) and the width (t) of ...