Network (CISNET) The Division of Cancer Control and Population Sciences (DCCPS) of the National Cancer Institute (NCI) invites applications from domestic and foreign applicants to support collaborative research using simulation and other modeling techniques to describe the impact of interventions in population-based settings that will shed light on U.S. population-based trends. It is well known...

The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a detailed sequence and population genetic analysis of a 29.5-kb common human deletion polymorphism that removes the APOBEC3B gene. We developed a PCR-based genotyping assay, characterized 1,277 human diver...

Section 1110 of the Social Security Act provides for a cooperative research grants program. The grants given by the Social Security Administration (SSA) under this program are to nonprofit organizations for research in the broad area of social security. Reports on six recently completed grants projects are summarized below, accompanied by a list of completed SSA research grants projects, with t...

Background: There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often specific to tissue type, developmental stage, environmental condition, or disease state. Accurate analysis of microarray expression data and design of new arrays for alternative splicing require assessment of probes at t...

Uppermost among the many concerns of young researchers is acquiring funding for beginning a career as a clinician-scientist. This chapter is targeted specifically at those individuals considering an academic physician-scientist career and those on the verge of becoming independent researchers. In Section I, Drs. Poncz and Iannone discuss the Mentored Career Development Award (K08). They summari...

Background: Although the sequence of events leading to wound repair has been described at the cellular and, to a limited extent, at the protein level this process has yet to be fully elucidated. Genome wide transcriptional analysis tools promise to further define the global picture of this complex progression of events. Study Design: This study was part of a placebo-controlled double-blind clin...

The Japan Society for the Promotion of Science (JSPS) conducts fellowship programs for foreign researchers to promote international cooperation in and mutual understanding through scientific research in Japan. These programs provide opportunities for U.S. researchers to conduct cooperative research under their host researchers. Research applications are accepted at the John E. Fogarty Internati...

The authors of the abstracts below will receive a diploma. The authors of the abstracts below will receive a cheque of 1000, free congress registration and a diploma.

Background: The effect of sleep on the risk of developing diabetes has not been explored in an Asian population. The objective of this study is to investigate the effect of self-reported sleep duration and sleep quality on the risk of developing diabetes in a prospective cohort in Japan. Methods: Data were analyzed from the cohort of participants in a High-risk and Population Strategy for Occup...

Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear equations, the conventional approach is to first numerically integrate the model, and then, in a second a posteriori step, check for consistency with experimental constraints. Hence, only single parameter sets can be c...