background: granulocyte colony stimulating factors (gcsf) are high cost agents commonly recommended for primary and secondary prophylaxis of chemotherapy-induced neutropenia and febrile neutropenia. gcsfs have been shown to be beneficial in some patient subgroups, although they are probably overused in clinical settings. the american society of clinical oncology (asco) guidelines summarize curr...

OBJECTIVES As in software product lifecycle, the effort spent in maintaining medical knowledge in guidelines can be reduced, if modularization, formalization and tracking of domain knowledge are employed across the guideline development phases. METHODS We propose to exploit and combine knowledge templates with medical background knowledge from existing thesauri in order to produce reusable bu...

Measurement of provider adherence to a guideline-based decision support system (DSS) presents a number of important challenges. Establishing a causal relationship between the DSS and change in concordance requires consideration of both the primary intention of the guideline and different ways providers attempt to satisfy the guideline. During our work with a guideline-based decision support sys...

This proposal focuses on the research question on how to develop a system that produces a formalized guideline. The output of this research project on the one hand, helps the medical personal in consulting and in their decision-making process and, on the other hand, fills the gap between the CPGs and their computer-interpretable representations. We use a document-centric model approach, which g...

2015 Guidelines for Perioperative Practice Last revised: July 2014. Copyright © 2015 AORN, Inc. All rights reserved. T he Guideline for Preoperative Patient Skin Antisepsis has been approved by the AORN Guidelines Advisory Board. It was presented as a proposed guideline for comments by members and others. The guideline is effective August 15, 2014. The recommendations in the guideline are inten...

Clinical practice guidelines are one of the foundations of efforts to improve health care. In 1999, we authored a paper about methods to develop guidelines. Since it was published, the methods of guideline development have progressed both in terms of methods and necessary procedures and the context for guideline development has changed with the emergence of guideline clearing houses and large s...

Evidence-based clinical guidelines require frequent updates due to research and technology advances. The quality of guideline updates can be improved if the knowledge underlying the guideline text is explicitly modelled using the so-called guideline patterns (GPs), mappings between a text fragment and a formal representation of its corresponding medical knowledge. Ontology-driven extraction of ...

Medical guidelines are hard to formalise because of their inherent fragmentary nature. Because of this, a formalism where details of guideline text are omitted is justified. In this paper, we describe medical histories and expectations and illustrate them with a number of examples from the Dutch breast cancer guideline. We applied our approach to an assumptionbased argumentation system for its ...

In this paper, we propose a formal theory to describe the development of medical guideline text in detail, but at a sufficiently high level abstraction, in such way that essential elements of the guidelines are highlighted. We argue that because of the fragmentary nature of medical guidelines, an approach where details in guideline text are omitted is justified. The different aspects of a guide...

©2016 8872147 Canada Inc. or its licensors CMAJ 1 Organizations around the world produce clinical practice guidelines at an astonishing pace, with great effort and at substantial cost.1 Unfortunately, despite broad dissemination efforts, large gaps remain between guideline recommendations and real-world practice across health systems, practitioner and patient types, and diseases.2 Conventional ...