Previous studies indicate that Matricaria chamomilla (MC), a folk remedy plant, is very useful in the treatment of spasmogenic bowel diseases but the way of its action is not clear. For this purpose, we studied the effect of MC extract on the electrically activation in Guinea-Pig ileum in an invitro model. We used guinea pig in this study. After of kill, we brouhght out a piece of ileum and fix...

sodium valproate (sv), an antiepileptic drug has several mechanism of action. it inhibits voltage sensitive na+ channels and reduces intracellular na accumulation. these actions are similar to that of both phenytoin and carbamazepine. we have investigated the direct cardiac action of sv and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. the guinea-pig atrium was dissect...

Onion (Allium Cepa) contains high levels of flavonoids. Although there are many studies indicating the inhibitory effects of flavonoids on xanthine oxidase, there is no report on the effect of onion on this enzyme. Therefore, in the present study, the inhibitory effects of onion on xanthine oxidase are investigated. Fresh filtered juice of onion was prepared and its inhibitory effect on guine...

A number of studies have suggested that attentional control skills required to perform 2 tasks concurrently become impaired with age (A. A. Hartley, 1992; J. M. McDowd & R. J. Shaw, 2000). A. A. Hartley (2001) recently observed that the age-related differences in dual-task performance were larger when the 2 tasks required similar motor responses. The present study examined the extent to which a...

In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both...

Sodium valproate (SV), an antiepileptic drug has several mechanism of action. It inhibits voltage sensitive Na+ channels and reduces intracellular Na accumulation. These actions are similar to that of both phenytoin and carbamazepine. We have investigated the direct cardiac action of SV and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. The guinea-pig atrium was dissect...

The present studies were carried out on the brains of adult guinea pigs, Dunkin-Hartley strain. On the basis of preparations, they were stained according to the Nissl and the Klüver-Barrera method's; a short description of the cytoarchitectonics and the characteristics of the rubral cells were written. The red nucleus (RN) of the guinea pig is 1.2 mm in length. Three cellular parts in RN, and t...

Since, the most susceptible laboratory animal to Foot–and–Mouth disease virus (FMDV) is guinea pig, and then one milliliter of FMDV type (O) concentrations of 106-106.5 TCID50was inoculated intradermally (ID) to 10 plantar surface of guinea pig (right side). Guinea pig adapted virus has been prepared after generalization phase, and then one milliliter of virus was inoculated intradermally to 30...

carum carvi (cc) is a grassy plant which is believed to have several therapeutic effects, including anti-asthmatic properties. we have therefore studied the bronchodilatory and anticholinergic effects of this plant. the bronchodilatory effects of the aqueous extract (ae), macerated extract (me), essential oil (eo), and 4µm theophylline (t) in comparison with saline (s) were examined by their re...

the β2-adrenergic effects of macerated extract, aqueous extract, ethanol extract, and essential oil of carum copticum, 5 nm propranolol, and saline were tested by performing cumulative log concentration-response curves of isoprenaline-induced relaxation of precontracted isolated guinea pig tracheal chains in three different conditions including: non-incubated (group 1, n=9) incubated with 1 µm ...