The Babesia bovis MSA-1, MSA-2b and MSA-2c are members of the variable merozoite surface antigen (VMSA) family, they are encoded surface proteins that are proposed to mediate the initial attachment of the merozoite to the host erythrocyte so this protein are targeted for vaccine and drug design. So the aim of this study is to give an outlook for MSA-1, MSA-2b and MSA-2c proteins using bioinform...

We have been interested in the construction of a vesicle-based Protocell Model. We already reported a self-reproducing giant vesicle (GV) system in which GVs grew and divided to daughter GVs with almost the same size if a membrane precursor was added to a dispersion of GVs containing a catalyst [1]. We showed that robust self-reproduction of GVs continued over several generations, as revealed b...

Modern Standard Arabic (MSA) is the formal language in most Arabic countries. Arabic Dialects (AD) or daily language differs from MSA especially in social media communication. However, most Arabic social media texts have mixed forms and many variations especially between MSA and AD. This paper aims to bridge the gap between MSA and AD by providing a framework for the translation of texts of soc...

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar circuits. It has been suggested that primary oligodendroglial α-synucleinopathy may represent a trigger in the pathogenesis of MSA, but the mechanisms...

Multiple system atrophy (MSA) is a fatal rapidly progressive α-synucleinopathy, characterized by α-synuclein accumulation in oligodendrocytes. It is accepted that the pathological α-synuclein accumulation in the brain of MSA patients plays a leading role in the disease process, but little is known about the events in the early stages of the disease. In this study we aimed to define potential ro...

1 Markov Random Field Model The following section will outline the mathematical model in our contact prediction method that is essentially identical to the plmDCA (Ekeberg et al., 2013) and GREMLIN (Kamisetty et al., 2013) methods. We eliminate transitive interactions in the observed interaction network by learning a generative model of the MSA using a Markov Random Field (MRF). Assuming we hav...

Multiple sequence alignments have primary role in several domains of modern molecular biology such as protein 3D structure/function prediction, phylogeny inference, molecular function, intermolecular interactions and many other common tasks in sequence analysis. Presently, many tools to construct multiple sequence alignments are available but none of them is accurate for all types of data sets....

OBJECTIVES To identify maternal and infant characteristics associated with reduced growth velocity (GV) in extremely premature newborns. METHODS We evaluated 1,187 infants born between 23 and 27 weeks' gestation at 14 institutions between 2002 and 2004 who survived until day 28 to identify the maternal and infant characteristics associated with a GV and caloric intake in the lowest quartile. ...

OBJECTIVE The A1C-Derived Average Glucose (ADAG) study demonstrated a linear relationship between HbA(1c) and mean plasma glucose (MPG). As glucose variability (GV) may contribute to glycation, we examined the association of several glucose variability indices and the MPG-HbA(1c) relationship. RESEARCH DESIGN AND METHODS Analyses included 268 patients with type 1 diabetes and 159 with type 2 ...