ابتلای یکی از اعضای خانواده به بیماری مزمن، بر روابط، نقش‌ها، سلسله مراتب و به‌طور کلی سیستم تأثیر می‌گذارد را برای مدیریت سازگاری با شرایط جدید، چالش‌هایی مواجه می‌کند. هدف این مرور ادبیات پژوهشی، شناسایی مسائلی است که در مزمن اعضا، آن رو‌به‌روست. بدین منظور، بررسی نظام‌مند مقالات چاپ‌شده زبان فارسی یا انگلیسی مجلات داخلی خارجی سال 201۴ (دی ۱۳۹۲) تاکنون، پایگاه‌های SID، Magiran، Google Scholar...

Intestinal graft-versus-host disease (I-GvHD) represents a life-threatening complication in allogeneic stem cell transplantation (SCT). Unfortunately, non-invasive validated diagnostic tools to diagnose I-GvHD, evaluate treatment response, and guide the duration of immunosuppression are still lacking. We employed standard ultrasound power Doppler follow up on pediatric intestinal GvHD. herein r...

Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...

background: the study attempts to assess the relationship between chimerism analysis using polymerase chain reaction of short tandem repeat (str) and the incidence of chronic graft versus host disease (gvhd) as well as survival. methods: the retrospective cohort included all patients who received allo-hsct between 2005 to 2013. data collected by day +100 were reviewed in terms of the incidence ...

Antigen-stimulated naïve T cells differentiate into effector and memory cells, of which resident (TRM) reside permanently in organ tissues. Involvement TRM has been indicated pathological conditions various skin diseases. CD122, is the β chain subunit interleukin (IL)-2 IL-15 receptors, expressed on immune including cells. To investigate whether CD122 signaling CD8+ mediates development mucocut...

Background: It is suggested that HA-1 mismatching among hematopoietic stem cell transplanted recipients-donors is associated with acute graft-versus-host disease (aGVHD). So the aim of this study was to evaluate HA-1 frequency and examine the correlation between HA-1 disparity and GVHD patients who received transplantation from a HLA-identical sibling. Samples and Methods: the DNA was extracted...