heamophilus influenzae type-b (hib) is a gram - negative pleomorphic bacterium that causes meningitis infections in children with the age of less than 5 years particularly in two years old infants. in the present study various isolates of heamophilus influenzae from infants suspected to meningitis were collected, identified, characterized and were used throughout our experiments. different cult...

A coagglutination assay using monoclonal antibody is described for the identification of Haemophilus influenzae type b. An immunoglobulin G2a monoclonal antibody, Hb-2, directed against a serotype-specific outer membrane protein of H. influenzae type b was adsorbed to Staphylococcus aureus Cowan 1 cells. In a dot enzyme immunoassay, Hb-2 reacted with 453 of 455 H. influenzae type b isolates and...

background: haemophilus influenzae type b (hib) has emerged as the predominant cause of meningitis in developing coun­tries wherever it has been studied using good microbiologic procedures, but data  regarding frequency, antimicrobial sus­ceptibility and preferable method for detection of haemophilus influenzae type b isolated from  iranian patients  were scarce. methods: one thousand and eight...

introduction : haemophilus influenzae type b (hib) is a gram negative bacterium and one of the causative agents of acute bacterial meningitis, especially in infants and children less than 5 years old. lipooligosaccharide (los), one of the virulence factors which plays an important role in pathogenesis of hib, has multiple applications in diagnosis and conjugate vaccines. in this study, los extr...

Heamophilus influenzae type-b (Hib) is a gram - negative pleomorphic bacterium that causes meningitis infections in children with the age of less than 5 years particularly in two years old infants. In the present study various isolates of Heamophilus influenzae from infants suspected to meningitis were collected, identified, characterized and were used throughout our experiments. Different cult...

background and objective: haemophilus influenzae type b (hib) is divided into two distinct genotypes, type i and type ii, based on the structure of capsular polysaccharides. the capsulation locus of haemophilus influenzae type b consists of three functionally distinct regions, designated regions 1 to 3. region iii contains hcsa and hcsb genes; however, notable sequence variation in this region ...

haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. the disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. despite the availability of new and more powerful antibiotics children with hib meningitis still suffer from high mortality or morbidity. the emergence of multir...

gations: chest x-ray normal; Hb 55%; W.B.C. 7,100 with normal diffierential; iron deficiency on the blood film; E.S.R. 138 mm. in one hour; Paul-Bunnell test negative. Blood culture revealed Haemophilus influenzae type B sensitive to all the usual antibiotics except sulphonamide. This child was treated with ampicillin and made a good recovery. My point in recording this case history is to empha...

background: streptococcus pneumoniae and haemophilus influenzae type b (hib) is a leading cause of bacterial pneumonia, meningitis, and sepsis in children under 5-year of age. this study aims to estimate potentially preventable number of cases and deaths caused by hib and pneumococcal in iran.materials and methods:we used the burden of diseases model estimates of the world health organization (...