We report three cases of unsuspected pregnancy during hysterosalpingography (HSG) with different outcomes. In the first two cases, menstrual history was wrongly relied upon and no pregnancy tests had been performed. However, even with a negative pregnancy test carried out prior to the investigation, as in the third case, this was proven not to be foolproof. The outcome of our pregnancies involv...

Sjögren's syndrome (SjS) is a chronic autoimmune disease that mainly targets the salivary and lacrimal glands. It has been controversial whether anti-muscarinic type 3 receptor (α-M3R) autoantibodies in patients with SjS inhibit intracellular trafficking of aquaporin-5 (AQP5), water transport protein, leading to secretory dysfunction. To address this issue, GFP-tagged human AQP5 was overexpress...

incidence of infertility is 15-20%. tubal and peritontal factors are responsible for 30-40% of infertility cases. in evaluation of infertile women, hysterosalpingography (hsg) is the first test in evaluating of fallopian tubes and laparoscopy is the gold standard test for diagnosing tubal problems and pelvic adhesions. in this study we evaluated 291 infertile couples. study is prospective, desc...

background: müllerian anomalies are associated with infertility. hysteroscopy as the gold standard for evaluating müllerian anomalies is an invasive, expensive and risky procedure which requires enough experience. transvaginal sonography (tvs) and hysterosalpingography (hsg) are less invasive procedures, but there is little known about the accuracy of these tests. the aim of this study was to e...

BACKGROUND Hysterosalpingography (HSG) is recommended as a first-line investigation for tubal assessment of infertile women. This investigation is not routinely available to GPs. AIM To explore the perceptions and attitudes of patients and health professionals to open access HSG for the initial management of infertile couples in general practice. DESIGN OF STUDY A nested qualitative study u...

PURPOSE A reduction in the dose, irradiated volume, and sensitivity of, in particular, normal tissue stem cells is needed to advance radiation therapy. This could be obtained with the use of particles for radiation therapy. However, the radiation response of normal tissue stem cells is still an enigma. Therefore, in the present study, we developed a model to investigate the in vitro response of...

OBJECTIVE Guidelines are not in agreement on the most effective diagnostic scenario for tubal patency testing; therefore, we evaluated the cost-effectiveness of invasive tubal testing in subfertile couples compared with no testing and treatment. DESIGN Cost-effectiveness analysis. SETTING Decision analytic framework. POPULATION Computer-simulated cohort of subfertile women. METHODS We e...

Hysterosalpingography (HSG) is the radiographic evaluation of the uterus and fallopian tubes that is used predominantly in the assessment of infertility and evaluation of abnormalities of the uterus and fallopian tubes. Some of the abnormalities that can be detected by HSG include congenital anomalies, polyps, leiomyomas, synechiae and adenomyosis. HSG is also used to evaluate any scarring on t...

Tuboperitoneal factors are responsible for about 30 to 40% of female infertility. The incidence of tubal disease in infertility varies from country to country. In India it has been estimated to be about 40%.1 The prevalence of pelvic inflammatory disease and genital tract tuberculosis are common in our country and hence the incidence of tubal factor in infertile women is high.2 There are variou...

PURPOSE Bispecific antibody (bsMAb) pretargeting procedures use divalent hapten-peptides to stabilize the binding of the hapten-peptide on tumor cells by a process known as the affinity enhancement system. The goal of this study was to determine if a divalent hapten-peptide could induce apoptosis by cross-linking bsMAb bound to CD20. METHODS Three forms of bsMAbs were prepared by coupling the...