نتایج جستجو برای: heart failure mesenchymal stromal cells cell transplantation

تعداد نتایج: 3000948  

Journal: :Haematologica 2015
Youshan Zhao Dong Wu Chengming Fei Juan Guo Shuncheng Gu Yang Zhu Feng Xu Zheng Zhang Lingyun Wu Xiao Li Chunkang Chang

Although it has been reported that mesenchymal stromal cells are unable to provide sufficient hematopoietic support in myelodysplastic syndrome, the underlying mechanisms remain elusive. In this study, we found that mesenchymal stromal cells from patients with myelodysplastic syndrome displayed a significant increase in senescence, as evidenced by their decreased proliferative capacity, flatten...

Journal: :Haematologica 2014
Alessandra Musso Silvia Catellani Paolo Canevali Sara Tavella Roberta Venè Silvia Boero Ivana Pierri Marco Gobbi Annalisa Kunkl Jean-Louis Ravetti Maria Raffaella Zocchi Alessandro Poggi

In this study, we analyzed the influence of mesenchymal stromal cells derived from lymph nodes of non-Hodgkin's lymphomas, on effector functions and differentiation of Vdelta (δ)2 T lymphocytes. We show that: i) lymph-node mesenchymal stromal cells of non-Hodgkin's lymphoma inhibit NKG2D-mediated lymphoid cell killing, but not rituximab-induced antibody-dependent cell-mediated cytotoxicity, exe...

Background & Aims: Myocardial infarction is a leading cause of human mortality in industrialized and developing societies. Limited restorative ability of of cardiomyocytes after ischemic changes can causes extensive damage lead to prominent chronic heart failure. At present, the application of certain drugs is touted as one of the main available approaches to inhibit the spread of the lesion an...

Journal: :Current stem cell research & therapy 2014
Yunfeng Lin

Numerous studies have been reported about the differentiation of mesenchymal stem cells (MSCs) into almost every cell type found in craniofacial tissues, such as bone, cartilage, tendon, ligament, muscle etc. Using MSCs as a cell source to engineer craniofacial tissue is becoming feasible. Some effects have been made to bridge the fundamental science and clinical application. Meanwhile, novel f...

Journal: :iranian biomedical journal 0
علیرضا خلعتبری ali reza khalatbary تقی طریحی taki tiraihi

background: recent reports demonstrated that intravenous route as a minimally invasive method, similar to direct injection, is suitable for bone marrow stromal cell (bmsc) transplantation. in this study, we made a comparison of intraspinal and intravenous route of bmsc administration to repair injured spinal cord tissue. methods: six groups of adult female rats were used in this study. laminect...

Journal: :مجله علوم اعصاب شفای خاتم 0
aida javadzadeh islamic azad university, mashhad branch, mashhad, iran mohammadreza khojaste islamic azad university, mashhad branch, mashhad, iran ali shariat razavi islamic azad university, mashhad branch, mashhad, iran sajad sahab negah a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iranshefa neuroscience research center, khatam alanbia hospital, tehran, iran

mesenchymal stem cells can be obtained from deferent tissues like adipose tissue, umbilical cord, placenta, skin, bone marrow, etc. these cells have regulatory effects on all types of immune cells such as dendritic cell, natural killers and lymphocytes. mesenchymal stem cells induce inhibitory phenotypes of antigen presenting cells (apcs) following their activity. they also change t cells pheno...

2013
Kapka Miteva Sophie Van Linthout Hans-Dieter Volk Carsten Tschöpe

Myocarditis is a common inflammatory cardiomyopathy, associated with cardiomyocyte apoptosis, which can lead to chronic left ventricular dysfunction. Under conventional heart failure therapy, inflammatory cardiomyopathy typically has a progressive course, indicating a need for alternative therapeutic strategies to improve long-term outcomes. Experimental and clinical studies consistently suppor...

Journal: :Veterinary surgery : VS 2011
Nakia D Spencer Jeffrey M Gimble Mandi J Lopez

Adult mesenchymal stromal cells are plastic-adherent cells that are self-renewing and have the capacity to differentiate into various tissue specific lineages. Stromal cells were initially discovered over 100 years ago and substantial insight into stromal cell identification, isolation, characterization, and differentiation has been made, including efforts to elucidate the factors involved in s...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید