نتایج جستجو برای: heart failure mesenchymal stromal cells cell transplantation

تعداد نتایج: 3000948  

Journal: :cell journal 0
narges labibzadeh mohsen emadedin roghayeh fazeli fatemeh mohseni seyedeh esmat hosseini reza moghadasali

objective: non:union: is defined as a minimum of 9 months since injury without any visible progressive signs of healing for 3 months. recent literature has shown that the application of mesenchymal stromal cells is safe, in vitro and in vivo, for treating long bone non:union:. the present study was performed to investigate the safety of mesenchymal stromal cell (msc) implantation in combination...

2017
Arjang Baygan Wictor Aronsson-Kurttila Gianluca Moretti Babylonia Tibert Göran Dahllöf Lena Klingspor Britt Gustafsson Bita Khoein Guido Moll Charlotta Hausmann Britt-Marie Svahn Magnus Westgren Mats Remberger Behnam Sadeghi Olle Ringden

Mesenchymal stromal cells (MSCs) are increasingly used in regenerate medicine. Placenta-derived decidual stromal cells (DSCs) are a novel therapy for acute graft-versus-host-disease (GVHD) and hemorrhagic cystitis (HC) after allogeneic hematopoietic stem cell transplantation (HSCT). DSCs are more immunosuppressive than MSCs. We assessed adverse events and safety using DSCs among 44 treated pati...

2016
Konstantin Tsoyi Sean R. R. Hall Jesmond Dalli Romain A. Colas Sailaja Ghanta Bonna Ith Anna Coronata Laura E. Fredenburgh Rebecca M. Baron Augustine M. K. Choi Charles N. Serhan Xiaoli Liu Mark A. Perrella

OBJECTIVES Mesenchymal stromal cells are being investigated as a cell-based therapy for a number of disease processes, with promising results in animal models of systemic inflammation and sepsis. Studies are ongoing to determine ways to further improve the therapeutic potential of mesenchymal stromal cells. A gas molecule that improves outcome in experimental sepsis is carbon monoxide. We hypot...

Journal: :Bosnian journal of basic medical sciences 2013
Amer Smajilagić Mufida Aljičević Amira Redžić Selma Filipović Alena Lagumdžija

Bone marrow mesenchymal cells have been identified as a source of pluripotent stem cells with multipotential potential and differentiation in to the different cells types such as are osteoblast, chondroblast, adipoblast. In this research we describe pioneering experiment of tissue engineering in Bosnia and Herzegovina, of the isolation and differentiation rat bone marrow stromal cells in to the...

Journal: :Cardiovascular research 2005
Erik B Friedrich Michael Böhm

Myocardial infarction and its consequences such as congestive heart failure continue to be a major cause of death in Western societies despite therapeutic advances made in recent years. A growing body of evidence indicates that cell-based strategies might have promising therapeutic potentials for cardiac revascularization and the restoration of cardiac function. In that respect, several recent ...

2014
Chantal Lechanteur Stefano Baila Michiel Etienne Janssens Olivier Giet Alexandra Briquet Etienne Baudoux Yves Beguin

Abbreviations: GMP: Good Manufacturing Practice; BM: Bone Marrow; HSC: Hematopoietic Stem Cells; MSC: Mesenchymal Stem/Stromal Cells; HCT: Hematopoietic Cell Transplantation; NK: Natural Killer; NOD/SCID: Non-Obese Diabetic/Severe Combined Immunodeficient mice; aGVHD: acute Graft Versus Host Disease; LTCG: Laboratory of Cell and Gene Therapy; EBMT: European group for Blood and Marrow Transplant...

Journal: : 2023

INTRODUCTION: The hierarchy of stromal progenitors from the bone marrow is poorly characterized; multipotent mesenchymal cells and colony-forming units fibroblasts are isolated in culture. Mesenchymal stem do not have a unique combination surface antigens, making it difficult to obtain pure population. expression nestin gene often used as marker these cells.
 AIM: To evaluate level charact...

2017
Iran Rashedi Nilesh Talele Xing-Hua Wang Boris Hinz Milica Radisic Armand Keating

MSCs are widely applied to regenerate heart tissue in myocardial diseases but when grown in standard two-dimensional (2D) cultures exhibit limited potential for cardiac repair and develop fibrogenic features with increasing culture time. MSCs can undergo partial cardiomyogenic differentiation, which improves their cardiac repair capacity. When applied to collagen patches they may improve cardia...

2017
Aruna V Vanikar Hargovind L Trivedi

[email protected] Abbreviations ABMR: Antibody Mediated Rejections; ADMSC: Adipose Tissue Derived Mesenchymal Stem Cells; AHG: Anti-Human Globulin; ASHI: American Society of Histocompatibility and Immunogenetics; CGN: Chronic Glomerulonephritis; CNI: Calcineurin Inhibitor; CRF: Chronic Renal Failure; DMEM: Dulbecco’s Modified Eagle’s Medium; DSA: Donor Specific Antibody; DST: Donor Specifi...

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