نتایج جستجو برای: heart failure mesenchymal stromal cells cell transplantation

تعداد نتایج: 3000948  

2012
Trixi Hollweck Christian Hagl Günther Eissner

Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this revi...

Journal: :iranian red crescent medical journal 0
farzaneh chehelcheraghi department of anatomical sciences, school of medicine, lorestan university of medical sciences, khorramabad, ir iran; department of anatomical sciences, school of medicine, lorestan university of medical sciences, khorramabad, ir iran. tel/fax: +98-2126127236 hossein eimani department of anatomical sciences, school of medicine, lorestan university of medical sciences, khorramabad, ir iran seyed homayoonsadraie department of anatomical sciences, school of medicine, lorestan university of medical sciences, khorramabad, ir iran giti torkaman department of physical therapy, faculty of medical sciences, tarbiat modares university, tehran, ir iran abdollah amini department of anatomy, medical faculty, shahid beheshti university of medical sciences, tehran, ir iran hamid alavi majd department of biostatistics, faculty of paramedicine, shahid beheshti university of medical sciences, tehran, ir iran

conclusions our findings showed that the treatment of flaps with bm-msc and aam transplantations significantly promoted flap survival compared to a control group. the viability of the flap was improved by combining bm-mscs with aam matrix scaffolds. materials and methods bm-mscs and aams were transplanted into subcutaneous tissue in the flap area. on the 7th postoperative day, the surviving fla...

Amir Tavakoli, Mohammad Abarkar, Mohammad Hejazi Mohammad Mahdi Dehghan Mohammad Molazem Nazanin Jafari Parviz Tajik, Pegah Abbasnia, Rouh-allah Mehdinavaz Aghdam Seyed Hosein Ahmadi Tafti

BACKGROUND: Bone marrow-derived mesenchymal cellscan transdifferentiate into Cardiomyocyte cells and improveheart function after transplantation. Since biomaterials canimprove the cell retention in the site, cell survival and differentiation,heart tissue engineering is now being explored as anapplied solution to support cell-based therapies and increasetheir efficacy for myocardial diseases. Ch...

Journal: :مجله علوم اعصاب شفای خاتم 0
ali shariat razavi medicine faculty, islamic azad university, mashhad branch, mashhad, iran mohammad reza khojasteh medicine faculty, islamic azad university, mashhad branch, mashhad, iran aida java zadeh medicine faculty, islamic azad university, mashhad branch, mashhad, iran sajad sahab negah a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iranshefa neuroscience research center, khatam alanbia hospital, tehran, iran

neuroinflammation has a significant role in induce of multiple sclerosis (ms) many approaches have been used to treat ms, but none of these methods have not been able to fully improve. one of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuro...

آی, جعفر , امیدفر, کبری , صدرالدینی, اسماعیل , عینی, لیلا , لاریجانی , باقر, مجیدزاده, کیوان , نقاش, نگار ,

Background: Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells, are considered as an important source of adult stem cells in tissue engineering and cell therapy. They are present in various tissues such as, endometrium as the supportive cells. According to anatomical position of endometrial mesenchymal stem cells that put them in neighborhood of the fetus, they m...

Journal: :international journal of molecular and cellular medicine 0
roya mehrasa university of guilan, rasht, iran.سازمان اصلی تایید شده: دانشگاه گیلان (guilan university) hamidreza vaziri university of guilan, rasht, iran.سازمان اصلی تایید شده: دانشگاه گیلان (guilan university) arezoo oodi blood transfusion research center, high institute for research and education in transfusion medicine,tehran iran.سازمان اصلی تایید شده: سازمان انتقال خون ایران (blood transfusion research center) mona khorshidfar blood transfusion research center, high institute for research and education in transfusion medicine,tehran iran.سازمان اصلی تایید شده: سازمان انتقال خون ایران (blood transfusion research center) mahin nikogoftar blood transfusion research center, high institute for research and education in transfusion medicine,tehran iran.سازمان اصلی تایید شده: سازمان انتقال خون ایران (blood transfusion research center) monireh golpour cellular and molecular biology research center, babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences)

umbilical cord blood (ucb) has been used for transplantation in the treatment of hematologic disorders as a source of hematopoietic stem cells (hscs). because of insufficient number of cord blood cd34+ cells, the expansion of these cells seems to be important for clinical application. mesenchymal stromal cells (mscs), playing an important role in hscs maintenance, were used as feeder layer. apo...

2017
Francesco Petrella Isabella Rimoldi Stefania Rizzo Lorenzo Spaggiari

Mesenchymal stromal cells are a population of undifferentiated multipotent adult cells possessing extensive self-renewal properties and the potential to differentiate into a variety of mesenchymal lineage cells. They express broad anti-inflammatory and immunomodulatory activity on the immune system and after transplantation can interact with the surrounding microenvironment, promoting tissue he...

Journal: :basic and clinical neuroscience 0
sam zarbakhsh fatemeh moradi mohammad taghi joghataei mehrdad bahktiari korosh mansouri mahmood abedinzadeh

introduction: transplantation of bone marrow stromal cells (bmscs) or schwann cells (scs) can increase axonal regeneration in peripheral nerve injuries. based on our previous investigations, the goal of the present work was to examine the individual and synergistic effects of the two different cell types in sciatic nerve injury . we pursued to evaluate the effects of bmscs and scs co-transplant...

Objective- Investigate myocardial performance after autologous adipose-derived (ASCs) mesenchymal stem cell differentiated under equiaxial cyclic strain, transplantation in rabbits with acute myocardial infarction (AMI). Design- Prospective, randomized experimental study Animals- 20 New Zealand White rabbits (2-3 kg) P...

2014
Mohamed Nemir Mélanie Metrich Isabelle Plaisance Mario Lepore Steeve Cruchet Corinne Berthonneche Alexandre Sarre Freddy Radtke Thierry Pedrazzini

AIMS In the adult heart, Notch signalling regulates the response to injury. Notch inhibition leads to increased cardiomyocyte apoptosis, and exacerbates the development of cardiac hypertrophy and fibrosis. The role of Notch in the mesenchymal stromal cell fraction, which contains cardiac fibroblasts and cardiac precursor cells, is, however, largely unknown. In the present study, we evaluate, th...

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