We consider the computational complexity of languages of symbolic dynamical systems. In particular, we study complexity hierarchies and membership of the non-uniform class P/poly. We prove: 1. For every time-constructible, non-decreasing function t(n) = ω(n), there is a symbolic dynamical system with language decidable in deterministic time O(nt(n)), but not in deterministic time o(t(n)). 2. Fo...

Seasonal influenza epidemics recur due to antigenic drift of envelope glycoprotein antigens and immune evasion of circulating viruses. Additionally, antigenic shift can lead to influenza pandemics. Thus, a universal vaccine that protects against multiple influenza virus strains could alleviate the continuing impact of this virus on human health. In mice, accelerated clearance of a new viral str...

We investigated the effect of long-term in vivo blockade of the ET-1 receptor subtype B (ET(B)) with A-192621, a selective ET(B) antagonist, on atrial and ventricular natriuretic peptide (NP) gene expression in deoxycorticosterone acetate (DOCA)-salt hypertension. In this model, stimulation of the cardiac natriuretic peptide (NP) and the endothelin system and suppression of the renin-angiotensi...

The influenza A virus nucleoprotein (NP) has been examined with regard to its RNA-binding characteristics. NP, purified from virions and devoid of RNA, bound synthetic RNAs in vitro and interacted with the ribonucleotide homopolymers poly(A), poly(G), poly(U), and poly(C) in a salt-dependent manner, showing higher binding affinity for polypyrimidine homopolymers. To map the NP regions involved ...

Heavy-duty vehicle hydrodynamic mechanical automatic transmission shifting operation system was designed, mathematical model of its simplified hydraulic system was established and simulation model of shifting operation system was established with AMESim, the simulation experiment was carried out, then oil pressure curves of each clutch hydraulic cylinder were obtained when giving forward gear o...

In the lattice formulation of the Heavy Quark Effective Theory, the value of the “classical velocity” v, as defined through the separation of the 4-momentum of a heavy quark into a part proportional to the heavy quark mass and a residual part which remains finite in the heavy quark limit (P = Mv + p), is different from its value as it appears in the bare heavy quark propagator (S -1 (p) = v·p)....