Reduced intrahepatic nitric oxide (NO) bioavailability and increased cyclooxygenase-1 (COX-1)-derived vasoconstrictor prostanoids modulate the hepatic vascular tone in cirrhosis. We aimed at investigating the reciprocal interactions between NO and COX in the hepatic endothelium of control and cirrhotic rats. NO bioavailability (DAF-FM-DA staining), superoxide (O(2)(-)) content (DHE staining), p...

In this work, we present new insights related to a debate on the morphological structure of hydroxyethyl cellulose (HEC) molecules when dissolved in water, i.e., whether HEC adopts a linear-flexible or a rod-like fibrillar configuration. We have employed “seven” rheological techniques to explore the viscoelastic properties of HEC solutions at different time and length scales. This work demonstr...

Real-time applications usually not only have a certain Packet Loss Ratio (PLR) requirement but also can have strict delay constraints. In the past, we proposed a Hybrid Error Correction (HEC) scheme with Packet Repetition (PR) technique for guaranteeing a certain PLR requirement under strict delay constraints. Unfortunately, the HEC-PR scheme can only work efficiently in multicast scenarios wit...

INTRODUCTION Few studies have described the inequalities in hormonal emergency contraception (HEC) use in developing countries. Thus, the main aim of this manuscript is to study socio-demographic inequalities in HEC use among Nicaraguan women, and to study if inequalities in HEC use arise from exposure to different forms of intimate partner violence (IPV). METHODS Data from a national cross-s...

In this paper, based on an ethnographic study, we show how management controllers craft their jobs through their daily practice and try to stretch their occupational identity. We adopt an original posture, developing a ‘negative ontology’ of practice, identity at work and professional competition. We argue that studying what individuals hide or despise in their daily activities enriches our und...

When the transition of operational activities is framed not as an instantaneous optimization problem but rather a series of incremental opportunistic choices formal continuous improvement (CI) capabilities prove useful. However, despite the well documented advantages of CI management, implementation failures are discouragingly high (Jazayeri and Hopper, 1999). In the quality literature the most...

High endothelial venules (HEV) allow rapid and selective lymphocyte trafficking from the blood into secondary lymphoid tissues. Here we report the expression profile of active genes in mouse high endothelial cells (HEC). HEC were first purified from mouse lymph nodes (LN) by magnetic cell sorting with MECA-79 mAb and a 3'-directed cDNA library that faithfully represents the composition of mRNA ...

Using a rat model we have previously proposed a role for fibronectin as an adhesive ligand on high endothelial cells (HEC) for recirculating lymphocytes. Lymphocyte adhesion to high endothelial cells was blocked by CS1 peptide (from the type IH connecting segment of fibronectin) and RGD-containing peptides using two different in vitro assays of lymphocyte-HEC recognition, the frozen section ass...

The development of human endometrial carcinoma (HEC) is a complex pathologic process involves several oncogenes and tumor suppressor genes. The full-length paired-box gene 2 (pax2), a recently discovered oncogene, promotes cell proliferation and growth and inhibits apoptosis of HEC cells. Here, we examined the effect of pax2 small interfering RNA (siRNA) on the growth of transplanted HEC cells ...

Cellulose based polymers have shown tremendous potential as drug delivery carrier for oral drug delivery system (DDS). Hydroxyethyl cellulose (HEC) and hydroxypropyl cellulose (HPC) are widely explored as excipients to improve the solubility of poorly water soluble drugs and to improve self-life of dosage form. This work is an attempt to modulate the physicochemical properties of these cellulos...